000 -LEADER |
fixed length control field |
05756nam a2200529 i 4500 |
001 - CONTROL NUMBER |
control field |
6813443 |
003 - CONTROL NUMBER IDENTIFIER |
control field |
IEEE |
005 - DATE AND TIME OF LATEST TRANSACTION |
control field |
20200413152855.0 |
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS |
fixed length control field |
m eo d |
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
fixed length control field |
cr cn |||m|||a |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
fixed length control field |
091104s2010 caua foab 000 0 eng d |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
International Standard Book Number |
9781598298765 (electronic bk.) |
020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
Canceled/invalid ISBN |
9781598298758 (pbk.) |
024 7# - OTHER STANDARD IDENTIFIER |
Standard number or code |
10.2200/S00212ED1V01Y200910TIS003 |
Source of number or code |
doi |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(CaBNVSL)gtp00536328 |
035 ## - SYSTEM CONTROL NUMBER |
System control number |
(OCoLC)472687323 |
040 ## - CATALOGING SOURCE |
Original cataloging agency |
CaBNVSL |
Transcribing agency |
CaBNVSL |
Modifying agency |
CaBNVSL |
050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
Classification number |
R857.T55 |
Item number |
A832 2010 |
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER |
Classification number |
610.28 |
Edition number |
22 |
100 1# - MAIN ENTRY--PERSONAL NAME |
Personal name |
Athanasiou, K. A. |
Fuller form of name |
(Kyriacos A.) |
245 10 - TITLE STATEMENT |
Title |
Articular cartilage tissue engineering |
Medium |
[electronic resource] / |
Statement of responsibility, etc. |
Kyriacos A. Athanasiou, Eric M. Darling, Jerry C. Hu. |
260 ## - PUBLICATION, DISTRIBUTION, ETC. |
Place of publication, distribution, etc. |
San Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : |
Name of publisher, distributor, etc. |
Morgan & Claypool Publishers, |
Date of publication, distribution, etc. |
c2010. |
300 ## - PHYSICAL DESCRIPTION |
Extent |
1 electronic text (xi, 168 p. : ill.) : |
Other physical details |
digital file. |
490 1# - SERIES STATEMENT |
Series statement |
Synthesis lectures on tissue engineering, |
International Standard Serial Number |
1944-0308 ; |
Volume/sequential designation |
# 3 |
538 ## - SYSTEM DETAILS NOTE |
System details note |
Mode of access: World Wide Web. |
538 ## - SYSTEM DETAILS NOTE |
System details note |
System requirements: Adobe Acrobat reader. |
500 ## - GENERAL NOTE |
General note |
Part of: Synthesis digital library of engineering and computer science. |
500 ## - GENERAL NOTE |
General note |
Series from website. |
504 ## - BIBLIOGRAPHY, ETC. NOTE |
Bibliography, etc. note |
Includes bibliographical references (p. 101-165). |
505 0# - FORMATTED CONTENTS NOTE |
Formatted contents note |
1. Hyaline articular cartilage -- Composition, structure and function of hyaline cartilage -- Biochemical composition -- Structure -- Function -- Articular chondrocytes -- Chapter concepts -- 2. Cartilage aging and pathology: the impetus for tissue engineering -- Cartilage formation -- Chondrocyte condensation and differentiation -- Hypertrophy and ossification -- Aging -- Cartilage injuries -- Osteochondral, chondral defects, and microfractures -- Causes of cartilage injuries -- Repair responses to cartilage injury -- Costs of articular cartilage injuries -- Osteoarthritis -- Osteoarthritic changes in the matrix -- Proliferation, catabolism, and cell death -- Costs of arthritis -- Motivation for tissue engineering -- Chapter concepts -- 3. In vitro tissue engineering of hyaline articular cartilage -- The need for in vitro tissue engineering -- Cell source -- Scaffold design -- Natural scaffolds -- Synthetic scaffolds -- Composite scaffolds -- Scaffoldless -- Bioactive molecules -- Growth factors -- Protein coating and peptide inclusion -- Catabolic and other structure modifying factors -- Mechanical stimulation -- Chapter concepts -- 4. Bioreactors -- Direct compression -- Hydrostatic pressure -- Shear bioreactors -- Contact shear -- Fluid shear -- Perfusion bioreactors -- "Low-shear" bioreactors -- Hybrid bioreactors -- Chapter concepts. |
505 8# - FORMATTED CONTENTS NOTE |
Formatted contents note |
5. Future directions -- Cell sources for the future -- A need for alternative cell sources -- Chondrogenic differentiation of MSCs and other adult cell sources -- Chondrogenic differentiation of ESC -- Assessment and design standards for tissue engineering -- Biomechanical techniques -- Design standards - functional improvement versus regeneration -- Current and emerging therapies -- Non-surgical methods -- Surgical methods -- Immune response, immunogenicity, transplants -- Cellular and humoral responses -- Allogeneic transplants -- Xenogeneic transplants -- Business aspects and regulatory affairs in cartilage tissue engineering -- Regulatory bodies -- Device classifications and pathways to market -- Currently available products -- Chapter concepts -- Bibliography. |
506 1# - RESTRICTIONS ON ACCESS NOTE |
Terms governing access |
Abstract freely available; full-text restricted to subscribers or individual document purchasers. |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Compendex |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
INSPEC |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Google scholar |
510 0# - CITATION/REFERENCES NOTE |
Name of source |
Google book search |
520 3# - SUMMARY, ETC. |
Summary, etc. |
Cartilage injuries in children and adolescents are increasingly observed, with roughly 20% of knee injuries in adolescents requiring surgery. In the US alone, costs of osteoarthritis are in excess of $65 billion per year (both medical costs and lost wages). Comorbidities are common with OA and are also costly to manage. Articular cartilage's low friction and high capacity to bear load makes it critical in the movement of one bone against another, and its lack of a sustained natural healing response has necessitated a plethora of therapies. Tissue engineering is an emerging technology at the threshold of translation to clinical use. Replacement cartilage can be constructed in the laboratory to recapitulate the functional requirements of native tissues. This book outlines the biomechanical and biochemical characteristics of articular cartilage in both normal and pathological states, through development and aging. It also provides a historical perspective of past and current cartilage treatments and previous tissue engineering efforts. Methods and standards for evaluating the function of engineered tissues are discussed, and current cartilage products are presented with an analysis on the United States Food and Drug Administration regulatory pathways that products must follow to market. This book was written to serve as a reference for researchers seeking to learn about articular cartilage, for undergraduate and graduate level courses, and as a compendium of articular cartilage tissue engineering design criteria. |
530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE |
Additional physical form available note |
Also available in print. |
588 ## - SOURCE OF DESCRIPTION NOTE |
Source of description note |
Title from PDF t.p. (viewed on November 4, 2009). |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Articular cartilage. |
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
Topical term or geographic name entry element |
Tissue engineering. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Darling, Eric M. |
700 1# - ADDED ENTRY--PERSONAL NAME |
Personal name |
Hu, Jerry C. |
730 0# - ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Synthesis digital library of engineering and computer science. |
830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
Uniform title |
Synthesis lectures on tissue engineering, |
International Standard Serial Number |
1944-0308 ; |
Volume/sequential designation |
# 3. |
856 42 - ELECTRONIC LOCATION AND ACCESS |
Materials specified |
Abstract with links to resource |
Uniform Resource Identifier |
http://ieeexplore.ieee.org/servlet/opac?bknumber=6813443 |