000			01982 a2200229 4500
003			OSt
005			20210707094040.0
008			210204b xxu||||| |||| 00| 0 eng d
020			_a9789811011399
040			_cIIT Kanpur
041			_aeng
082			_a547.1223 _bY1s
100			_aYadav, Veejendra K.
245			_aSteric and stereoelectronic effects in organic chemistry [Perpetual] _cVeejendra K. Yadav
260			_c2016 _aSingapore _bSpringer
300			_axi, 216p
520			_aThe steric and stereoelectronic effects control the rate and stereochemical outcome of reactions. Hence, a decent understanding of the related concepts is essential for successful synthetic planning. The book attempts to address several important issues related to these concepts in a simplified manner, and is intended for graduate students. It lays stress on the important aspects of steric and stereoelectronic effects and their control on the conformational profile and reactivity features. The book covers the geometrical requirements for reactions at saturated and unsaturated carbons in both cyclic and acyclic systems, and the resultant stereochemical features. The aspect of geometrical flexibility is also covered with a few examples involving intramolecular reactions. It deals with the facial selectivity of nucleophilic additions to acyclic and cyclic carbonyl compounds, and explains how the steric and stereoelectronic effects control the same. The work comments on allylic strains and their stereochemical control on different reactions with the related conformational control. It is a must read to understand the control elements, the prominent among these elements are spiro-conjugation, periselectivity, torquoselectivity, a-effect, Hammett’s substituent constants, Hammond postulate, and Curtin-Hammett principle.
650			_aChemistry, Organic
650			_aStereochemistry
856			_uhttps://link.springer.com/book/10.1007/978-981-10-1139-9
942			_cEBK
999			_c563586 _d563586