000			05244nam a2200613 i 4500
001			6813172
003			IEEE
005			20200413152853.0
006			m eo d
007			cr cn |||m|||a
008			090407s2009 caua foab 000 0 eng d
020			_a9781598298734 (electronic bk.)
020			_a9781598298727 (pbk.)
024	7		_a10.2200/S00186ED1V01Y200903TIS001 _2doi
035			_a(CaBNVSL)gtp00533832
035			_a(OCoLC)318064205
040			_aCaBNVSL _cCaBNVSL _dCaBNVSL
050		4	_aR857.T55 _bA833 2009
082	0	4	_a610.28 _222
100	1		_aAthanasiou, K. A. _q(Kyriacos A.)
245	1	0	_aEngineering the knee meniscus _h[electronic resource] / _cKyriacos A. Athanasiou and Johannah Sanchez-Adams.
260			_aSan Rafael, Calif. (1537 Fourth Street, San Rafael, CA 94901 USA) : _bMorgan & Claypool Publishers, _cc2009.
300			_a1 electronic text (83 p. : ill.) : _bdigital file.
490	1		_aSynthesis lectures on tissue engineering ; _v# 1
538			_aMode of access: World Wide Web.
538			_aSystem requirements: Adobe Acrobat reader.
500			_aPart of: Synthesis digital library of engineering and computer science.
500			_aSeries from website.
504			_aIncludes bibliographical references (p. 63-80).
505	0		_aStructure-function relationships of the knee meniscus -- Anatomy and development -- Anatomy of the knee meniscus -- Development of the knee meniscus -- Biochemical composition, structure, and function -- Regional variation -- Biochemical content -- Biomechanical properties and evaluation techniques -- Geometrical considerations -- Normal loading conditions -- Shock absorption -- Collagen organization -- Biphasic behavior -- Biomechanical evaluation -- Tension -- Compression -- Shear -- Cell types -- Cell classification -- Diversity of meniscus cells -- Cell synthetic properties -- Regional variation in synthetic profiles -- Mechanosensitivity of meniscus cells -- Pathophysiology and the need for tissue engineering -- Pathophysiology and injury -- Meniscus pathology -- Osteoarthritis and meniscal degeneration -- Tears of the meniscus -- Epidemiology of meniscus tears -- The meniscus healing problem -- Introduction -- Healing in the meniscus -- Characteristics of repair tissue -- Tissue engineering and historical perspectives -- Definition of tissue engineering -- Historical perspectives -- Functional tissue engineering and the meniscus -- Tissue engineering of the knee meniscus -- Bioreactors -- Introduction -- Direct compression -- Hydrostatic pressure -- Shear -- Ultrasound -- Combinations -- Application to meniscus engineering -- In vitro tissue engineering -- Introduction -- Cell source -- Growth factors -- Synthetic scaffolds -- Natural scaffolds -- Scaffold-free approaches -- In vivo tissue engineering -- Introduction -- Animal models -- Fibrin -- Synthetic scaffolds -- Natural scaffolds -- Current therapies and future directions -- Products and current therapies -- Products involving biological materials -- Other current therapies -- Design standards -- Determining design standards -- Primary standards -- Secondary standards -- Assessments for tissue engineered constructs -- Need for functional assessment -- Functionality index -- Variable considerations -- Bibliography.
506	1		_aAbstract freely available; full-text restricted to subscribers or individual document purchasers.
510	0		_aCompendex
510	0		_aINSPEC
510	0		_aGoogle scholar
510	0		_aGoogle book search
520	3		_aThe knee meniscus was once thought to be a vestigial tissue, but is now known to be instrumental in imparting stability, shock absorption, load transmission, and stress distribution within the knee joint. Unfortunately, most damage to the meniscus cannot be effectively healed by the body. Meniscus tissue engineering offers a possible solution to this problem by striving to create replacement tissue that may be implanted into a defect site. With a strong focus on structure-function relationships, this book details the essential anatomical, biochemical, and mechanical aspects of this versatile tissue and reviews current meniscus tissue engineering strategies and repair techniques. We have written this text such that undergraduate students, graduate students, and researchers will find it useful as a first foray into tissue engineering, a cohesive study of the meniscus, or a reference for meniscus engineering specifications.
530			_aAlso available in print.
588			_aTitle from PDF t.p. (viewed on April 7, 2009).
650		0	_aMeniscus (Anatomy)
650		0	_aTissue engineering.
690			_aMeniscus
690			_aTissue engineering
690			_aMeniscus biomechanics
690			_aMeniscus tears
690			_aFunctionality index
690			_aBioreactors
690			_aMeniscus cells
690			_aMeniscus vasculature
690			_aAlternate cell sources
700	1		_aSanchez-Adams, Johannah.
730	0		_aSynthesis digital library of engineering and computer science.
830		0	_aSynthesis lectures on tissue engineering ; _v# 1.
856	4	2	_3Abstract with links to resource _uhttp://ieeexplore.ieee.org/servlet/opac?bknumber=6813172
999			_c561671 _d561671