000 04400nam a22004815i 4500
001 978-0-387-68234-1
003 DE-He213
005 20161121231150.0
007 cr nn 008mamaa
008 100301s2007 xxu| s |||| 0|eng d
020 _a9780387682341
_9978-0-387-68234-1
024 7 _a10.1007/978-0-387-68234-1
_2doi
050 4 _aR856-857
072 7 _aMQW
_2bicssc
072 7 _aTEC009000
_2bisacsh
082 0 4 _a610.28
_223
100 1 _aThubrikar, Mano J.
_eauthor.
245 1 0 _aVascular Mechanics and Pathology
_h[electronic resource] /
_cby Mano J. Thubrikar.
264 1 _aBoston, MA :
_bSpringer US,
_c2007.
300 _aXXIII, 494 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aAtherosclerosis I -- Atherosclerosis II -- Structure and Mechanics of the Artery -- Pressure Vessel Principles -- Pressure Vessel Intersections -- Stress-Concentration in the Artery I -- Stress-Concentration in the Artery II -- Endothelial Cells and Low-Density Lipoproteins at the Branch -- Smooth Muscle Cells and Stretch -- Stress Reduction and Atherosclerosis Reduction -- The Vein Graft -- Anastomosis -- Anastomotic Aneurysms and Anastomotic Intimal Hyperplasia -- Intracranial Aneurysms -- Aortic Aneurysms -- Aortic Dissection.
520 _aVascular Mechanics and Pathology Mano J. Thubrikar, PhD, FAHA. Opening new doors for interdisciplinary research, Vascular Mechanics and Pathology establishes a correlation between vascular mechanics and pathology that could lead to the reduction of vascular diseases, as well as the development of new treatments. Vascular Mechanics and Pathology focuses on the artery and arterial diseases. As the fundamental functions of the artery are to serve as a conduit of blood flow and as a container of blood pressure, Vascular Mechanics and Pathology describes both the general principles and the occurrence of stress concentration at the pressure vessel junctions and examines the role of beta-blockers in the reduction of atherosclerosis and related complications. This cutting-edge work presents the use of veins as arterial grafts and discusses the role of vein valves in graft stenosis. Vascular Mechanics and Pathology illustrates aneurysm formation, growth, and rupture, using pressure vessel principles. This new work details the investigation of, amongst other topics, aortic dissection, showing for the first time that the aortic root mechanics plays a vital role in the development of this pathology. Key topics: Atherosclerosis Structure and Mechanics of the Artery Pressure Vessel Principles Pressure Vessel Intersections Stress Concentration in the Artery Endothelial Cells and Low Density Lipoproteins at the Branch Smooth Muscle Cells and Stretch Stress Reduction and Atherosclerosis Reduction The Vein Graft Anastomosis Anastomotic Aneurysms and Anastomotic Intimal Hyperplasia Intracranial Aneurysms Aortic Aneurysms Aortic Dissection Vascular Mechanics and Pathology is essential reading for cardiovascular researchers, surgeons, cardiologists, pathologists, radiologists, neurosurgeons, anatomists, students in biomedical engineering, and manufacturers of medical devices. About the Author: Dr. Mano J. Thubrikar has been with Edwards Lifesciences since December 2004. Previously, he was the Director of the Biomedical Engineering Program at the Heineman Medical Research Center at Carolinas Medical Center, Charlotte, NC. Dr. Thubrikar is a recipient of the Research Career Development Award from the National Institute of Health, the Certificate of Merit awarded by the New York Academy of Medicine, and the Minna-James Heineman Stiftung Research Award for Outstanding Research Achievements in the area of Life Sciences.
650 0 _aEngineering.
650 0 _aNeurosciences.
650 0 _aCardiology.
650 0 _aPathology.
650 0 _aBiomedical engineering.
650 1 4 _aEngineering.
650 2 4 _aBiomedical Engineering.
650 2 4 _aNeurosciences.
650 2 4 _aCardiology.
650 2 4 _aPathology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387338163
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-68234-1
912 _aZDB-2-ENG
950 _aEngineering (Springer-11647)
999 _c509515
_d509515