000 03058nam a22005055i 4500
001 978-3-540-49858-2
003 DE-He213
005 20161121231048.0
007 cr nn 008mamaa
008 100301s2007 gw | s |||| 0|eng d
020 _a9783540498582
_9978-3-540-49858-2
024 7 _a10.1007/978-3-540-49858-2
_2doi
050 4 _aQH505
072 7 _aPHVN
_2bicssc
072 7 _aPHVD
_2bicssc
072 7 _aSCI009000
_2bisacsh
082 0 4 _a571.4
_223
245 1 0 _aTopology in Molecular Biology
_h[electronic resource] /
_cedited by Michail Ilych Monastyrsky.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2007.
300 _aXIV, 238 p. 118 illus., 6 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aBiological and Medical Physics, Biomedical Engineering,
_x1618-7210
505 0 _aTopology in Biology: From DNA Mechanics to Enzymology -- Monte Carlo Simulation of DNA Topological Properties -- Dynamics of DNA Supercoiling -- From Tangle Fractions to DNA -- Linear Behavior of the Writhe Versus the Number of Crossings in Rational Knots and Links -- Combinatories and Topology of the ?-Sandwich and ?-Barrel Proteins -- The Structure of Collagen -- Euler Characteristic, Dehn–Sommerville Characteristics, and Their Applications -- Hopf Fibration and Its Applications -- Multi-Valued Functionals, One-Forms and Deformed de Rham Complex -- The Spectral Geometry of Riemann Surfaces.
520 _aThe book presents a class of new results in molecular biology for which topological methods and ideas are important. These include: the large-scale conformation properties of DNA; computational methods (Monte Carlo) allowing the simulation of large-scale properties of DNA; the tangle model of DNA recombination and other applications of Knot theory; dynamics of supercoiled DNA and biocatalitic properties of DNA; the structure of proteins; and other very recent problems in molecular biology. The text also provides a short course of modern topology intended for the broad audience of biologists and physicists. The authors are renowned specialists in their fields and some of the new results presented here are documented for the first time in monographic form.
650 0 _aPhysics.
650 0 _aMolecular biology.
650 0 _aBioinformatics.
650 0 _aBiophysics.
650 0 _aBiological physics.
650 1 4 _aPhysics.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aMolecular Medicine.
650 2 4 _aBioinformatics.
700 1 _aMonastyrsky, Michail Ilych.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540234074
830 0 _aBiological and Medical Physics, Biomedical Engineering,
_x1618-7210
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-49858-2
912 _aZDB-2-PHA
950 _aPhysics and Astronomy (Springer-11651)
999 _c507985
_d507985