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001 978-0-387-49989-5
003 DE-He213
005 20161121231039.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387499895
_9978-0-387-49989-5
024 7 _a10.1007/978-0-387-49989-5
_2doi
050 4 _aQC450-467
050 4 _aQC718.5.S6
072 7 _aPNFS
_2bicssc
072 7 _aPDND
_2bicssc
072 7 _aSCI078000
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082 0 4 _a621.36
_223
245 1 0 _aHandbook of Molecular Force Spectroscopy
_h[electronic resource] /
_cedited by Aleksandr Noy.
264 1 _aBoston, MA :
_bSpringer US,
_c2008.
300 _aXII, 300 p. 150 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aSurface force apparatus measurements of molecular forces in biological adhesion (Deborah Leckband, Univ. of Illinois, Urbana-Champaign) -- Force spectroscopy with optical and magnetic tweezers (Richard Conroy, Harvard University) -- Chemical Force Microscopy 1: Nanoscale probing of fundamental chemical interactions (Aleksandr Noy, LLNL, Dmitry V. Vezenov, Harvard University, and Charles M. Lieber, Harvard University) -- Chemical Force Microscopy 2: Interactions in complex molecular assemblies (Dmitry V. Vezenov, Harvard University, Aleksandr Noy, LLNL, and Charles M. Lieber, Harvard University) -- Dynamic force spectroscopy with the atomic force microscope (Phil Williams, University of Nottingham) -- Simulation in force spectroscopy (David L. Patrick, Western Washington University) -- Probe tip functionalization: applications to chemical force microscopy (Craig D. Blanchard, Albert Loui, and Timothy V. Ratto, LLNL) -- The dynamical response of proteins under force -- (Kirstine L. Anderson, Sheena E. Radford, D. Alastair Smith, and David J. Brockwell, University of Leeds) -- Counting and breaking single bonds: Dynamic force spectroscopy in tethered single molecule systems (Todd A. Sulchek, Raymond W. Friddle, and Aleksandr Noy, LLNL) -- Direct mapping of intermolecular interaction potentials (Paul D. Ashby, MIT).
520 _a"...Noy's Handbook of Molecular Force Spectroscopy is both a timely and useful summary of fundamental aspects of molecular force spectroscopy, and I believe it would make a worthwhile addition to any good scientific library. New research groups that are entering this field would be well advisedto study this handbook in detail before venturing into the exciting and challenging world of molecular force spectroscopy." Matthew F. Paige, University of Saskatchewan, Journal of the American Chemical Society Modern materials science and biophysics are increasingly focused on studying and controlling intermolecular interactions on the single-molecule level. Molecular force spectroscopy was developed in the past decade as the result of several unprecedented advances in the capabilities of modern scientific instrumentation, and defines a number of techniques that use mechanical force measurements to study interactions between single molecules and molecular assemblies in chemical and biological systems. Examples of these techniques, which typically target a specific range of experimental systems and geometries, include atomic force microscopy, optical tweezers, surface forces apparatus, and magnetic tweezers. With contributions by internationally renowned scientists, Handbook of Molecular Force Spectroscopy is a comprehensive, state-of-the-art review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The Handbook presents reviews of fundamental physical concepts of loading single and multiple chemical bonds on the nanometer scale, covers practical aspects of modern single-molecule level techniques, and describes several representative applications of force spectroscopy to the study of chemical and biological processes. Computer modeling of force spectroscopy experiments is addressed as well. In sum, this volume is an authoritative guide to planning, understanding, and analyzing modern molecular force spectroscopy experiments with an emphasis on biophysical research.
650 0 _aPhysics.
650 0 _aBiochemistry.
650 0 _aSolid state physics.
650 0 _aSurfaces (Physics).
650 0 _aInterfaces (Physical sciences).
650 0 _aThin films.
650 0 _aBiophysics.
650 0 _aBiological physics.
650 0 _aSpectroscopy.
650 0 _aMicroscopy.
650 0 _aNanotechnology.
650 1 4 _aPhysics.
650 2 4 _aSpectroscopy and Microscopy.
650 2 4 _aSolid State Physics.
650 2 4 _aSurface and Interface Science, Thin Films.
650 2 4 _aNanotechnology.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aBiochemistry, general.
700 1 _aNoy, Aleksandr.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387499871
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-49989-5
912 _aZDB-2-PHA
950 _aPhysics and Astronomy (Springer-11651)
999 _c507768
_d507768