000 04506nam a22005415i 4500
001 978-0-8176-4503-8
003 DE-He213
005 20161121231029.0
007 cr nn 008mamaa
008 100301s2006 xxu| s |||| 0|eng d
020 _a9780817645038
_9978-0-8176-4503-8
024 7 _a10.1007/978-0-8176-4503-8
_2doi
050 4 _aQH301-705
072 7 _aPSA
_2bicssc
072 7 _aSCI086000
_2bisacsh
082 0 4 _a570
_223
100 1 _aBellouquid, Abdelghani.
_eauthor.
245 1 0 _aMathematical Modeling of Complex Biological Systems
_h[electronic resource] :
_bA Kinetic Theory Approach /
_cby Abdelghani Bellouquid, Marcello Delitala.
264 1 _aBoston, MA :
_bBirkhäuser Boston,
_c2006.
300 _aXII, 188 p. 47 illus.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aModeling and Simulation in Science, Engineering and Technology
505 0 _aOn the Modelling of Complex Biological Systems -- Mathematical Frameworks of the Generalized Kinetic (Boltzmann) Theory -- Modelling the Immune Competition and Applications -- On the Cauchy Problem -- Simulations, Biological Interpretations, and Further Modelling Perspectives -- Models with Space Structure and the Derivation of Macroscopic Equations -- Critical Analysis and Forward Perspectives.
520 _aThis book describes the evolution of several socio-biological systems using mathematical kinetic theory. Specifically, it deals with modeling and simulations of biological systems—comprised of large populations of interacting cells—whose dynamics follow the rules of mechanics as well as rules governed by their own ability to organize movement and biological functions. The authors propose a new biological model for the analysis of competition between cells of an aggressive host and cells of a corresponding immune system. Because the microscopic description of a biological system is far more complex than that of a physical system of inert matter, a higher level of analysis is needed to deal with such complexity. Mathematical models using kinetic theory may represent a way to deal with such complexity, allowing for an understanding of phenomena of nonequilibrium statistical mechanics not described by the traditional macroscopic approach. The proposed models are related to the generalized Boltzmann equation and describe the population dynamics of several interacting elements (kinetic population models). The particular models proposed by the authors are based on a framework related to a system of integro-differential equations, defining the evolution of the distribution function over the microscopic state of each element in a given system. Macroscopic information on the behavior of the system is obtained from suitable moments of the distribution function over the microscopic states of the elements involved. The book follows a classical research approach applied to modeling real systems, linking the observation of biological phenomena, collection of experimental data, modeling, and computational simulations to validate the proposed models. Qualitative analysis techniques are used to identify the prediction ability of specific models. The book will be a valuable resource for applied mathematicians as well as researchers in the field of biological sciences. It may be used for advanced graduate courses and seminars in biological systems modeling with applications to collective social behavior, immunology, and epidemiology. .
650 0 _aLife sciences.
650 0 _aApplied mathematics.
650 0 _aEngineering mathematics.
650 0 _aMathematical models.
650 0 _aBiomathematics.
650 1 4 _aLife Sciences.
650 2 4 _aLife Sciences, general.
650 2 4 _aMathematical Modeling and Industrial Mathematics.
650 2 4 _aMathematical and Computational Biology.
650 2 4 _aApplications of Mathematics.
650 2 4 _aGenetics and Population Dynamics.
650 2 4 _aPhysiological, Cellular and Medical Topics.
700 1 _aDelitala, Marcello.
_eauthor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780817643959
830 0 _aModeling and Simulation in Science, Engineering and Technology
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-8176-4503-8
912 _aZDB-2-SMA
950 _aMathematics and Statistics (Springer-11649)
999 _c507534
_d507534