000 | 03156nam a22005295i 4500 | ||
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001 | 978-3-540-77768-7 | ||
003 | DE-He213 | ||
005 | 20161121230849.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2008 gw | s |||| 0|eng d | ||
020 |
_a9783540777687 _9978-3-540-77768-7 |
||
024 | 7 |
_a10.1007/978-3-540-77768-7 _2doi |
|
050 | 4 | _aRC902-918 | |
072 | 7 |
_aMJR _2bicssc |
|
072 | 7 |
_aMED055000 _2bisacsh |
|
082 | 0 | 4 |
_a616.61 _223 |
100 | 1 |
_aMoritz, Karen M. _eauthor. |
|
245 | 1 | 0 |
_aFactors Influencing Mammalian Kidney Development: Implications for Health in Adult Life _h[electronic resource] / _cby Karen M. Moritz, Marelyn Wintour-Coghlan, M. Jane Black, John F. Bertram, Georgina Caruana. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008. |
|
300 |
_aIX, 79 p. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aAdvances in Anatomy Embryology and Cell Biology, _x0301-5556 ; _v196 |
|
505 | 0 | _aMorphological Development of the Mammalian Kidney -- Genetic Regulation of Metanephric Development -- Abnormalities of Renal Development in the Human -- Methodology to Examine Kidney Development -- Development of Function in the Fetus -- Nephron Endowment -- Developmental Programming of the Kidney -- Future Directions. | |
520 | _aIn this monograph the authors have emphasized a number of important concepts in mammalian kidney development. Emphasis has been put on methodology so that the reader can understand how certain results or conclusions were reached and what the optimal methods for reliable results to be obtained are. In addition, as well as descriptions of the morphology there is information on the genetic basis of the structural development. In addition much attention has been paid to how nephron number may be altered by changes in the environment of the developing kidney and to the consequences for the remaining nephron gene expression and kidney function when total nephron number is altered. The consequences for the health of the adult, upon the formation of an adult kidney with altered nephron number and (potentially) gene expression, can be quite serious. The epigenetic mechanisms by which such changes can occur are introduced as a very fertile field for future investigation. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aHuman genetics. | |
650 | 0 | _aHuman physiology. | |
650 | 0 | _aNephrology. | |
650 | 1 | 4 | _aMedicine & Public Health. |
650 | 2 | 4 | _aNephrology. |
650 | 2 | 4 | _aHuman Physiology. |
650 | 2 | 4 | _aHuman Genetics. |
700 | 1 |
_aWintour-Coghlan, Marelyn. _eauthor. |
|
700 | 1 |
_aBlack, M. Jane. _eauthor. |
|
700 | 1 |
_aBertram, John F. _eauthor. |
|
700 | 1 |
_aCaruana, Georgina. _eauthor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540777670 |
830 | 0 |
_aAdvances in Anatomy Embryology and Cell Biology, _x0301-5556 ; _v196 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-540-77768-7 |
912 | _aZDB-2-SME | ||
950 | _aMedicine (Springer-11650) | ||
999 |
_c505081 _d505081 |