000			03789nam a22006135i 4500
001			978-3-540-49070-8
003			DE-He213
005			20161121230846.0
007			cr nn 008mamaa
008			100301s2008 gw | s |||| 0|eng d
020			_a9783540490708 _9978-3-540-49070-8
024	7		_a10.1007/978-3-540-49070-8 _2doi
050		4	_aR895-920
072		7	_aMMPH _2bicssc
072		7	_aMMP _2bicssc
072		7	_aMED008000 _2bisacsh
082	0	4	_a616.0757 _223
245	1	0	_aLate Effects of Cancer Treatment on Normal Tissues _h[electronic resource] / _cedited by Philip Rubin, Louis S. Constine, Lawrence B. Marks, Paul Okunieff.
246	3		_aWith contributions by numerous experts
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008.
300			_aXXII, 140 p. 68 illus., 30 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMedical Radiology, Radiation Oncology, _x0942-5373
505	0		_aRadiation (and Medical) Biosurveillance -- Medical Countermeasures to Radiation Injury -- Ionizing Radiation and the Endothelium -- Inflammation and Cell Adhesion Molecules are Involved in Radiation-Induced Lung Injury -- Volume Effects in Radiation Damage to Rat Lung -- The Role of Imaging in the Study of Radiation-Induced Normal Tissue Injury -- Screening for Cardiovascular Disease in Survivors of Thoracic Radiation -- Hypoxia-Mediated Chronic Normal Tissue Injury -- Prevention and Treatment of Radiation Injuries -- Second Malignancies as a Consequence of Radiation Therapy -- Using Quality of Life Information to Rationally -- Cancer-Related Fatigue as a Late Effect: -- Normal Tissue TNM Toxicity Taxonomy -- Cancer Survivorship Research:.
520			_aThe search for the most favorable therapeutic ratio – at which ablation of cancer is achieved while normal tissues are conserved – has been modern radiation oncology’s equivalent of the quest for the Holy Grail. Our awareness of the late effects of radiation grew during the past century as new modalities were introduced. Heightened normal tissue reactions accompanied the higher rates of cancer ablation achieved by escalation of radiation doses, accelerated fractionated radiotherapy, and aggressive concurrent chemotherapy and radiation regimens. This volume is based on the LENT V NCI-sponsored meeting held in May 2004 and the CURED I conference held in 2006. Written by experts in the field, it addresses a number of critical topics relating to late effects, such as mechanisms of injury, the role of screening, options for interventions, second malignancies, and prevention. It is hoped that it will assist the reader in understanding how to prevent and treat the long-term side-effects of irradiation.
650		0	_aMedicine.
650		0	_aRadiology.
650		0	_aRadiotherapy.
650		0	_aInternal medicine.
650		0	_aOncology.
650		0	_aPediatrics.
650		0	_aSurgical oncology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aImaging / Radiology.
650	2	4	_aRadiotherapy.
650	2	4	_aOncology.
650	2	4	_aSurgical Oncology.
650	2	4	_aInternal Medicine.
650	2	4	_aPediatrics.
700	1		_aRubin, Philip. _eeditor.
700	1		_aConstine, Louis S. _eeditor.
700	1		_aMarks, Lawrence B. _eeditor.
700	1		_aOkunieff, Paul. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540490692
830		0	_aMedical Radiology, Radiation Oncology, _x0942-5373
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-540-49070-8
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c505021 _d505021