000 04864nam a22005415i 4500
001 978-3-211-69459-6
003 DE-He213
005 20161121230845.0
007 cr nn 008mamaa
008 100611s2008 au | s |||| 0|eng d
020 _a9783211694596
_9978-3-211-69459-6
024 7 _a10.1007/978-3-211-69459-6
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
245 1 0 _aRecombinant Human Erythropoietin (rhEPO) in Clinical Oncology
_h[electronic resource] :
_bScientific and Clinical Aspects of Anemia in Cancer /
_cedited by Mohammad Resa Nowrousian.
250 _aSecond, Revised and Enlarged Edition.
264 1 _aVienna :
_bSpringer Vienna,
_c2008.
300 _aXVIII, 866 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aPhysiology of erythropoiesis -- Biology of EPO and EPO-receptor -- The role of erythropoietin receptor expression on tumor cells -- Problems associated with erythropoietin receptor determination on tumor cells -- Definition, classification and characterization of anemia in cancer -- Pathophysiology of anemia in cancer -- Prevalence and incidence of anemia and risk factors for anemia in patients with cancer -- Significance of anemia in cancer chemotherapy -- Incidence and impact of anemia in radiation oncology -- Relationship between hemoglobin levels and tumor oxygenation -- Tumor hypoxia and therapeutic resistance -- Symptoms of anemia -- Impact of anemia and red blood cell transfusion on organ function -- Relationship of hemoglobin, fatigue, and quality of life in anemic cancer patients -- When to use red blood cell transfusions in cancer patients with solid tumours? -- Pharmacology, pharmacokinetics and safety of recombinant human erythropoietin preparations -- Epoetin treatment of anemia associated with multiple myeloma and non-Hodgkin’s lymphoma -- rhEPO in anemic patients with solid tumors and chemotherapy — efficacy and safety -- Early intervention with recombinant human erythropoietin for chemotherapy-induced anemia -- Recombinant human erythropoietin (rhEPO) therapy in myelodysplasia -- Prediction of response to rhEPO in the anemia of cancer -- rhEPO in hematopoietic stem cell transplantation -- Treatment of anemia with rhEPO in radiation oncology -- Recombinant human erythropoietin in pediatric oncology -- rhEPO in surgical oncology -- Erythropoiesis, iron metabolism and iron supplementation during erythropoietin therapy -- Are there risks for use of iron in cancer patients? -- Metabolic and physiologic effects of rhEPO in anemic cancer patients -- Effects of rhEPO on quality of life in anemic cancer patients -- Thrombosis during therapy with erythropoiesis stimulating agents in cancer -- The effect of rhEPO on survival in anemic cancer patients -- From bench to bedside: Neuroprotective effects of erythropoietin -- rhEPO in patients with anemia and congestive heart failure -- Cost-effectiveness of treating cancer anaemia.
520 _aAnemia is a frequent complication of cancer and its treatment. It produces many symptoms and significantly impairs metabolic and physiologic functions as well as patients' activity, well-being and quality of life. Life expectancy is also affected. This book, now being published in its second edition, comprehensively presents the current knowledge on anemia in cancer and its treatment with rhEPO. Future developments are also discussed. Based on updated and new chapters, including a broader spectrum of topics, outstanding international experts describe the scientific and clinical aspects of anemia in various fields of oncology and give diagnostic and therapeutic recommendations on when and how to use rhEPO. The book, considered as a standard work, will again serve as an essential source of information for radiotherapists, medical oncologists, hematologists, internists, pediatricians, surgeons, specialists in transfusion and laboratory medicine, and pharmacologists.
650 0 _aMedicine.
650 0 _aPharmacology.
650 0 _aRadiotherapy.
650 0 _aBlood transfusion.
650 0 _aHematology.
650 0 _aOncology.
650 0 _aSurgery.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aRadiotherapy.
650 2 4 _aHematology.
650 2 4 _aSurgery.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aBlood Transfusion Medicine.
700 1 _aNowrousian, Mohammad Resa.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783211252239
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-211-69459-6
912 _aZDB-2-SME
950 _aMedicine (Springer-11650)
999 _c504981
_d504981