000			03942nam a22005175i 4500
001			978-1-60327-116-5
003			DE-He213
005			20161121230842.0
007			cr nn 008mamaa
008			100505s2008 xxu| s |||| 0|eng d
020			_a9781603271165 _9978-1-60327-116-5
024	7		_a10.1007/978-1-60327-116-5 _2doi
050		4	_aRC648-665.2
072		7	_aMJG _2bicssc
072		7	_aMED027000 _2bisacsh
082	0	4	_a616.4 _223
245	1	4	_aThe Metabolic Syndrome _h[electronic resource] : _bEpidemiology Clinical Treatment and Underlying Mechanisms / _cedited by Barbara Caleen Hansen, George A. Bray.
264		1	_aTotowa, NJ : _bHumana Press, _c2008.
300			_aXII, 402 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aContemporary Endocrinology
505	0		_aMetabolic Syndrome—Past and Future -- Metabolic Syndrome—Past and Future -- Epidemilogy And Clinical Treatment: Issues In Defining And Treating The Metabolic Syndrome -- Metabolic Syndrome -- The Role of Obesity in Insulin Resistance -- Treatment of the Metabolic Syndrome with Weight Loss, Exercise, Hormones, and Surgery -- Insulin Resistance, Metabolic Syndrome, and Cardiovascular Disease -- The Sympatho-Adrenal System in the Metabolic Syndrome -- Endothelial Function, Inflammation, and Dyslipidemia -- Insulin Action and Endothelial Function -- Macro- and Microvascular Disease in an Insulin-Resistant Pre-Diabetic Animal Model -- High-Sensitivity C-Reactive Protein and the Metabolic Syndrome -- Insulin Signaling in Adipocytes and the Role of Inflammation -- Insulin Resistance and Dyslipidemia -- Insulin—Secretion and Action: Underlying Mechanisms of the Metabolic Syndrome -- Pancreatic Islet Pathophysiology and Pathology in Obesity -- Glucagon-like Peptides and Insulin Sensitivity -- The Relationship Between the Insulin Receptor Substrates and Metabolic Disease -- Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase -- Fat Feeding and Muscle Fat Deposition Eliciting Insulin Resistance -- Alterations in Atypical Protein Kinase C Activation in Insulin Resistance Syndromes -- The Liver, Glucose Homeostasis, and Insulin Action in Type 2 Diabetes Mellitus -- Chronomics of the Metabolic Syndrome.
520			_aWith an extraordinary need for early intervention and prevention to slow or halt its progression, Metabolic Syndrome is one of the most challenging health problems. Only through an understanding of the science underlying this syndrome can successful interventions be developed and implemented. In The Metabolic Syndrome: Epidemiology, Clinical Treatment, and Underlying Mechanisms, the writers stimulate new thinking concerning underlying mechanisms and encourage heightened efforts to develop new therapeutics, potentially targeting uniquely intersecting pathways. Developing this new synthesis and analysis of the Metabolic Syndrome will bring together the viewpoints of epidemiologists, physiologists, molecular biologists/biochemists, and clinicians toward understanding the current state of knowledge of both the causes and consequences of the Metabolic Syndrome.
650		0	_aMedicine.
650		0	_aInternal medicine.
650		0	_aCardiology.
650		0	_aDiabetes.
650		0	_aEndocrinology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aEndocrinology.
650	2	4	_aDiabetes.
650	2	4	_aInternal Medicine.
650	2	4	_aCardiology.
700	1		_aHansen, Barbara Caleen. _eeditor.
700	1		_aBray, George A. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588297389
830		0	_aContemporary Endocrinology
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-60327-116-5
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c504927 _d504927