000			03933nam a22005175i 4500
001			978-1-60327-079-3
003			DE-He213
005			20161121230842.0
007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9781603270793 _9978-1-60327-079-3
024	7		_a10.1007/978-1-60327-079-3 _2doi
050		4	_aRC870-923.2
050		4	_aRC875-899.5
072		7	_aMJS _2bicssc
072		7	_aMED088000 _2bisacsh
082	0	4	_a616.6 _223
245	1	0	_aProstate Cancer _h[electronic resource] : _bSignaling Networks, Genetics, and New Treatment Strategies / _cedited by Richard G. Pestell, Marja T. Nevalainen, Michael Milken.
264		1	_aTotowa, NJ : _bHumana Press, _c2008.
300			_aXVI, 456 p. 33 illus., 11 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aCurrent Clinical Oncology
505	0		_aHistopathology and Molecular Biology of Prostate Atrophy -- Epigenetic Gene Silencing in Prostate Cancer -- Inherited Genetic Changes in Prostate Cancer -- Prostate Molecular Oncogenesis -- Somatic Genetic Changes in Prostate Cancer -- Androgen Receptor in Prostate Cancer Progression -- Epigenetic Modification and Acetylation of Androgen Receptor Regulate Prostate Cellular Growth -- Estrogen Receptor ? and ? in the Regulation of Normal and Malignant Prostate Epithelium -- Estrogen Action in Normal Prostate Epithelium and in Prostate Cancer -- Hypoxia-Inducible Factor 1 in the Angiogenesis of Prostate Cancer -- Signal Transduction by the Ras–MAP Kinase Pathway in Prostate Cancer Progression -- Transcription Factors STAT5 and STAT3 -- Role of PI3K–Akt and PTEN in the Growth and Progression of Prostate Cancer -- New Perspectives in Prediction of Clinical Outcome of Prostate Cancer -- New Directions in Radiation Therapy of Prostate Cancer -- The Current Knowledge of Hormonal Therapy in the Treatment of Prostate Cancer -- Advances in Surgical Intervention of Prostate Cancer -- Targeted Therapy Trials for Prostate Cancer -- New Perspectives on Chemotherapy in Prostate Cancer -- Concluding Remarks.
520			_aAward winning authors present a comprehensive review of new perspectives in prostate cancer research and open up new directions in the clinical management of prostate cancer. In, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies", the authors focus on the biology, genetics, molecular signaling networks in the disease process, and recent advances in the treatment of prostate cancer. This state-of-the-art title provides key insights into cutting edge advances in prostate cancer research, such as laparoscopic radical prostatectomy, and offers a critical evaluation and discussion of opportunities for development of novel therapies for prostate cancer. Clinical trials that have not been covered or evaluated in any other books currently available are also discussed. Invaluable to physicians and researchers, "Prostate Cancer: Signaling Networks, Genetics, and New Treatment Strategies" provides a comprehensive translational resource as well as an important source of information for prostate cancer patients.
650		0	_aMedicine.
650		0	_aInternal medicine.
650		0	_aOncology.
650		0	_aUrology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aUrology.
650	2	4	_aOncology.
650	2	4	_aInternal Medicine.
700	1		_aPestell, Richard G. _eeditor.
700	1		_aNevalainen, Marja T. _eeditor.
700	1		_aMilken, Michael. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588297419
830		0	_aCurrent Clinical Oncology
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-60327-079-3
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c504924 _d504924