000 04165nam a22004935i 4500
001 978-1-59745-374-5
003 DE-He213
005 20161121230841.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9781597453745
_9978-1-59745-374-5
024 7 _a10.1007/978-1-59745-374-5
_2doi
050 4 _aRE1-994
072 7 _aMJQ
_2bicssc
072 7 _aMED063000
_2bisacsh
082 0 4 _a617.7
_223
245 1 0 _aVisual Transduction and Non-Visual Light Perception
_h[electronic resource] /
_cedited by Joyce Tombran-Tink, Colin J. Barnstable.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2008.
300 _aXI, 509 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aOphthalmology Research
505 0 _aEvolution of the Visual System -- An Organ of Exquisite Perfection -- Photoreceptor Structure, Function, and Development -- Development of the Foveal Specialization -- An Update on the Regulation of Rod Photoreceptor Development -- The Retinal Pigment Epithelium and the Visual Cycle -- Photoreceptor—RPE Interactions -- Molecular Biology of IRBP and Its Role in the Visual Cycle -- Visual Signaling in the Outer Retina -- Regulation of Photoresponses by Phosphorylation -- The cGMP Signaling Pathway in Retinal Photoreceptors and the Central Role of Photoreceptor Phosphodiesterase (PDE6) -- Rhodopsin Structure, function, and Involvement in Retinitis Pigmentosa -- Multiple Signaling Pathways Govern Calcium Homeostasis in Photoreceptor Inner Segments -- The Transduction Channels of Rod and Cone Photoreceptors -- Rhodopsins in Drosophila Color Vision -- INAD Signaling Complex of Drosophila Photoreceptors -- Visual Processing in the Inner Retina -- Visual Signal Processing in the Inner Retina -- Color Vision and Adaptive Processes -- Human Cone Spectral Sensitivities and Color Vision Deficiencies -- Luminous Efficiency Functions -- Cone Pigments and Vision in the Mouse -- Multifocal Oscillatory Potentials of the Human Retina -- Aging and Vision -- The Aging of the Retina -- Aging of the Retinal Pigment Epithelium -- Visual Transduction and Age-Related Changes in Lipofuscin -- Nonphotoreceptor Light Detection and Circadian Rhythms -- A Nonspecific System Provides Nonphotic Information for the Biological Clock -- The Circadian Clock: Physiology, Genes, and Disease.
520 _aRemarkable advances have contributed to revolutionizing the study of vertebrate vision. The first step to identifying objects and establishing spatial relationships is the visual transduction cascade, a process that underpins a wide range of ocular diseases and therapies. Toward that, Visual Transduction And Non-Visual Light Perception reveals not only how the eye evolved into an organ of vision, but also describes how molecular mechanisms of key molecules (such as transducins, phosphodiesterases, and CyclicGMP metabolizing enzymes) operate in the phototransduction cascade. In this groundbreaking text, experts also explain mechanisms for sensing readiation outside of the visible wavelengths -- a good example of the limitations of the human sensory systems. Comprehensive and penetrating, Visual Transduction And Non-Visual Light Perception brings together the developmental, structural, and molecular mechanisms of the visual transduction cascade and is an invaluable text for everyone conducting research in the visual system.
650 0 _aMedicine.
650 0 _aMolecular biology.
650 0 _aOphthalmology.
650 0 _aCell biology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOphthalmology.
650 2 4 _aCell Biology.
650 2 4 _aMolecular Medicine.
700 1 _aTombran-Tink, Joyce.
_eeditor.
700 1 _aBarnstable, Colin J.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781588299574
830 0 _aOphthalmology Research
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-59745-374-5
912 _aZDB-2-SME
950 _aMedicine (Springer-11650)
999 _c504893
_d504893