000			03148nam a22003975i 4500
001			978-1-4020-8486-7
003			DE-He213
005			20161121230839.0
007			cr nn 008mamaa
008			100301s2008 ne | s |||| 0|eng d
020			_a9781402084867 _9978-1-4020-8486-7
024	7		_a10.1007/978-1-4020-8486-7 _2doi
050		4	_aR1
072		7	_aMB _2bicssc
072		7	_aMED000000 _2bisacsh
082	0	4	_a610 _223
245	1	0	_aEssentials of Clinical Research _h[electronic resource] / _cedited by Stephen P. Glasser.
264		1	_aDordrecht : _bSpringer Netherlands, _c2008.
300			_aXV, 360 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aI -- Clinical Research: Definitions, “Anatomy and Physiology,” and the Quest for “Universal Truth” -- to Clinical Research and Study Designs -- Clinical Trials -- Alternative Interventional Study Designs -- Postmarketing Research -- The United States Federal Drug Administration (FDA) and Clinical Research -- The Placebo and Nocebo Effect -- Recruitment and Retention -- Data Safety and Monitoring Boards (DSMBs) -- Meta-Analysis -- II -- Research Methods for Genetic Studies -- Research Methods for Pharmacoepidemiology Studies -- Implementation Research: Beyond the Traditional Randomized Controlled Trial -- Research Methodology for Studies of Diagnostic Tests -- III -- Statistical Power and Sample Size: Some Fundamentals for Clinician Researchers -- Association, Cause, and Correlation -- Bias, Confounding, and Effect Modification -- It’s All About Uncertainty -- Grant Writing -- IV -- The Media and Clinical Research -- Mentoring and Advising -- Presentation Skills: How to Present Research Results.
520			_aThis book is designed to provide the “student” interested in clinical research a foundation upon which to build more advanced study. The book focuses on clinical trials, in contrast to the many excellent textbooks that address epidemiological research. With the recent interest in patient oriented research, this book should provide a knowledge base that is not necessarily covered in other texts. Chapters discussing the FDA’s role in clinical research, Data Safety and Monitoring Boards, Postmarketing studies, the use of placebo controls, and a focus on clinical trials illustrates this point. In addition, new types of clinical research are evolving, and as such, this book discusses genetic, pharmacoepidemiologic, and implementation research. Finally, chapters on tips on how to write a grant, the mentoring process, and how to present ones research results are unique to this book.
650		0	_aMedicine.
650	1	4	_aMedicine & Public Health.
650	2	4	_aMedicine/Public Health, general.
700	1		_aGlasser, Stephen P. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781402084850
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-4020-8486-7
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c504848 _d504848