000 | 03520nam a22005775i 4500 | ||
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001 | 978-3-540-31916-0 | ||
003 | DE-He213 | ||
005 | 20161121230823.0 | ||
007 | cr nn 008mamaa | ||
008 | 100806s2005 gw | s |||| 0|eng d | ||
020 |
_a9783540319160 _9978-3-540-31916-0 |
||
024 | 7 |
_a10.1007/b98750 _2doi |
|
050 | 4 | _aRB1-214 | |
072 | 7 |
_aMMF _2bicssc |
|
072 | 7 |
_aMED067000 _2bisacsh |
|
082 | 0 | 4 |
_a616.07 _223 |
245 | 1 | 0 |
_aReactions, Processes _h[electronic resource] : _bOxidants and Antioxidant Defense Systems / _cedited by Tilman Grune. |
246 | 3 | _aWith contribution by numerous experts | |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2005. |
|
300 |
_aXVI, 240 p. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aThe Handbook of Environmental Chemistry, _x1433-6855 ; _v2O |
|
505 | 0 | _aHans Nohl, Andrey Kozlov, Lars Gille, and Katrin Staniek: Endogenous oxidant-generating systems -- Peter Schroeder and Jean Krutmann: Environmental oxidative stress -- Helen Griffith: Chemical modifications of Biomolecules by oxidants -- Kelvin J.A. Davies: Broad spectrum of cellular reactions to oxidative stress -- Tilman Grune, Peter Schroeder, and Hans K. Biesalski: Low-molecular weight antioxidants -- Juan Sastre, Federico Pallardo, and Jose Vina: The glutathione system -- Grzegorz Bartosz: Superoxide dismutases and catalase -- Bente Riis, Henrik Poulsen: DNA-repair mechanisms -- Diana Poppek and Tilman Grune: Protein repair and degradation -- L.-O. Klotz: Metabolic regulation and gene expression in response to oxidative stress -- Enrique Cadenas and Alberto Boveris: Mitochondrial free radical production, antioxidant defenses and cell signaling. | |
520 | _aOxidative stress is one of the major symptoms accompanying physiological functions and numerous diseases. Oxidants and free radicals are connected with diseases such as cancer, diabetes, infectious, cardiovascular and neurodegenerative diseases and also in the aging process itself. Therefore, comprehensive knowledge of the underlying mechanisms of oxidant and free radical production and the defence against this permanent threat to cells is important for the understanding of many physiological and pathophysiological processes. This book overviews the basic mechanisms of oxidant formation and antioxidant defences. In addition, the formation of oxidants and their detoxification, the damage of macromolecules and the major repair and removal systems will be highlighted. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aPharmacology. | |
650 | 0 | _aOccupational medicine. | |
650 | 0 | _aPathology. | |
650 | 0 | _aEcology. | |
650 | 0 | _aGeoecology. | |
650 | 0 | _aEnvironmental geology. | |
650 | 0 | _aEcotoxicology. | |
650 | 1 | 4 | _aMedicine & Public Health. |
650 | 2 | 4 | _aPathology. |
650 | 2 | 4 | _aEcotoxicology. |
650 | 2 | 4 | _aGeoecology/Natural Processes. |
650 | 2 | 4 | _aOccupational Medicine/Industrial Medicine. |
650 | 2 | 4 | _aPharmacology/Toxicology. |
650 | 2 | 4 | _aEcology. |
700 | 1 |
_aGrune, Tilman. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540224235 |
830 | 0 |
_aThe Handbook of Environmental Chemistry, _x1433-6855 ; _v2O |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/b98750 |
912 | _aZDB-2-EES | ||
950 | _aEarth and Environmental Science (Springer-11646) | ||
999 |
_c504469 _d504469 |