000			05282nam a22005655i 4500
001			978-88-470-0807-6
003			DE-He213
005			20161121230812.0
007			cr nn 008mamaa
008			100301s2008 it | s |||| 0|eng d
020			_a9788847008076 _9978-88-470-0807-6
024	7		_a10.1007/978-88-470-0807-6 _2doi
050		4	_aQD431-431.7
072		7	_aPSBC _2bicssc
072		7	_aSCI007000 _2bisacsh
082	0	4	_a572.6 _223
245	1	0	_aDioxygen Binding and Sensing Proteins _h[electronic resource] : _bA Tribute to Beatrice and Jonathan Wittenberg / _cedited by Martino Bolognesi, Guido di Prisco, Cinzia Verde.
264		1	_aMilano : _bSpringer Milan, _c2008.
300			_aXII, 264 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aProtein Reviews ; _v9
505	0		_aIntroduction: A Dedication to Beatrice and Jonathan Wittenberg -- Reflections on Beatrice and Jonathan Wittenberg -- The Wittenbergs: A Personal Appreciation -- A Crystallographer’s Perspective on the 2/2Hb Family -- The Phylogeny and Structural Properties of 2/2 Haemoglobins -- Reexamining Data from the Past Related to the Evolution of the Functional Properties of the Haemoglobins of the Teleost Fish -- Evolutionary Physiology of Oxygen Secretion in the Eye of Fishes of the Suborder Notothenioidei -- Mutagenic Studies on the Origins of the Root Effect -- Redox Reactions of Cross-linked Haemoglobins with Oxygen and Nitrite -- Bis-histidyl Ferric Adducts in Tetrameric Haemoglobins -- Cooperativity and Ligand-linked Polymerisation in Scapharca Tetrameric Haemoglobin -- Human Serum Haeme-albumin: An Allosteric ‘Chronosteric’ Protein -- T- and R-state Tertiary Relaxations in Sol-gel Encapsulated Haemoglobin -- From O2 Diffusion into Red Blood Cells to Ligand Pathways in Globins -- Myoglobin Strikes Back -- The Bilatarian Sea Urchin and the Radial Starlet Sea Anemone Globins Share Strong Homologies with Vertebrate Neuroglobins -- Whale Rider: The Co-occurrence of Haemoglobin and Haemocyanin in Cyamus scammoni -- Neuroglobin and Other Nerve Haemoglobins -- Ever Surprising Nematode Globins -- Microbial Haemoglobins: Proteins at the Crossroads of Oxygen and Nitric Oxide Metabolism.
520			_aFollowing their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments. This book is dedicated to Jonathan’s and Bea’s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come. Praise for the Wittenbergs and their lasting contributions to research: "Oxygen: a two-atom molecule, but what a wealth of chemistry, and what implications for life! I was always convinced that the deep roots of such a simple statement have constantly inspired the seminal work of the Wittenbergs on the mechanisms of oxygen diffusion and on the varied cellular roles of dozens of different haeme proteins." (Martino Bolognesi) "All of us who study oxygen transport and all who value good science are in their debt." (Ken van Holde) "Beatrice and Jonathan Wittenberg have inspired generations of scientists to explore the mysteries of haeme proteins. Their papers…prompted discussions… in the 1970s and led to investigations on numerous invertebrate myoglobins and haemoglobins…" (Nora Terwilliger) "I was one of many PhD students in the late 1980s who were weaned on the seminal work by the Wittenbergs on myoglobin-facilitated oxygen diffusion. Before reading that article, myoglobin and oxygen diffusion was a mystery to me. With their work, biochemistry and physiology became a dynamic presence in my life." (Cinzia Verde).
650		0	_aLife sciences.
650		0	_aBiochemistry.
650		0	_aProteins.
650		0	_aCell biology.
650		0	_aEvolutionary biology.
650		0	_aMicrobiology.
650	1	4	_aLife Sciences.
650	2	4	_aProtein Science.
650	2	4	_aBiochemistry, general.
650	2	4	_aLife Sciences, general.
650	2	4	_aEvolutionary Biology.
650	2	4	_aMicrobiology.
650	2	4	_aCell Biology.
700	1		_aBolognesi, Martino. _eeditor.
700	1		_aPrisco, Guido di. _eeditor.
700	1		_aVerde, Cinzia. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9788847008069
830		0	_aProtein Reviews ; _v9
856	4	0	_uhttp://dx.doi.org/10.1007/978-88-470-0807-6
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c504198 _d504198