000			03686nam a22004935i 4500
001			978-4-431-30130-1
003			DE-He213
005			20161121230812.0
007			cr nn 008mamaa
008			100301s2007 ja | s |||| 0|eng d
020			_a9784431301301 _9978-4-431-30130-1
024	7		_a10.1007/978-4-431-30130-1 _2doi
050		4	_aQH573-671
072		7	_aPSF _2bicssc
072		7	_aSCI049000 _2bisacsh
082	0	4	_a571.6 _223
245	1	0	_aNuclear Dynamics _h[electronic resource] : _bMolecular Biology and Visualization of the Nucleus / _cedited by Kyosuke Nagata, Kunio Takeyasu.
264		1	_aTokyo : _bSpringer Japan, _c2007.
300			_aXII, 279 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aVisual Biology of Nuclear Dynamics: From Micro- to Nano-dynamics of Nuclear Components -- Nuclear Envelope: Nanoarray Responsive to Aldosterone -- Mitotic Chromosome Segregation Control -- Breakdown and Reformation of the Nuclear Envelope -- Functional Organization and Dynamic Aspects of Nucleoli During the Cell Cycle -- Dynamics, Roles, and Diseases of the Nuclear Membrane, Lamins, and Lamin-binding Proteins -- Gene Selectors Consisting of DNA-Binding Proteins, Histories, and Histone-Binding Proteins Regulate the Three Major Stages of Gene Expression -- Dynamic Chromatin Loops and the Regulation of Gene Expression -- Nuclear Architecture: Topology and Function of Chromatin- and Non-Chromatin Nuclear Domains -- Regulation of Chromatin Structure by Curved DNA: How Activator Binding Sites Become Accessible -- Actin-Related Proteins Involved in Nuclear and Chromatin Dynamics -- Effects of 5-Bromodeoxyuridine on Chromatin Structure -- Transcriptional Modulation by Nuclear Matrix Protein P130/MAT3 Associated with MAR/SAR -- Breaking and Tessellating the Contiguous Nuclear Genome -- Perspective—toward understanding the in situ genome function.
520			_aThe nuclear structure is not always stable but varies from hour to hour. Thus, it is important to capture dynamic changes of the structure and function from the viewpoint of molecular dynamics. Using the latest visualizing techniques in combination with biochemical and molecular biological methods, researchers from a broad range of fields of knowledge, including chromosomal structure, nuclear transfer, RNA, nuclear membrane, transcription, and nuclear domain structures, provide an overview of the nuclear structure and current issues in nuclear dynamics. The dynamics of nuclear structures described in this book furnish the basis for a comprehensive understanding of how the higher-order organization and function of the nucleus is established and how it correlates with the expression of a variety of vital activities such as cell proliferation and differentiation. The resulting volume creates an invaluable source of reference for researchers in the field.
650		0	_aLife sciences.
650		0	_aBiotechnology.
650		0	_aBiochemical engineering.
650		0	_aBiochemistry.
650		0	_aCell biology.
650	1	4	_aLife Sciences.
650	2	4	_aCell Biology.
650	2	4	_aBiochemistry, general.
650	2	4	_aBiochemical Engineering.
650	2	4	_aBiotechnology.
700	1		_aNagata, Kyosuke. _eeditor.
700	1		_aTakeyasu, Kunio. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9784431300540
856	4	0	_uhttp://dx.doi.org/10.1007/978-4-431-30130-1
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c504176 _d504176