000			03373nam a22005055i 4500
001			978-3-540-76733-6
003			DE-He213
005			20161121230810.0
007			cr nn 008mamaa
008			100301s2008 gw | s |||| 0|eng d
020			_a9783540767336 _9978-3-540-76733-6
024	7		_a10.1007/978-3-540-76733-6 _2doi
050		4	_aQH573-671
072		7	_aPSF _2bicssc
072		7	_aSCI049000 _2bisacsh
082	0	4	_a571.6 _223
245	1	0	_aHydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes _h[electronic resource] / _cedited by Jan Tachezy.
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008.
300			_aXII, 287 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aMicrobiology Monographs, _x1862-5576 ; _v9
505	0		_aAnaerobic Eukaryotes in Pursuit of Phylogenetic Normality: the Evolution of Hydrogenosomes and Mitosomes -- Protein Import into Hydrogenosomes and Mitosomes -- Structure of the Hydrogenosome -- Hydrogenosomes of Anaerobic Ciliates -- Metabolism of Trichomonad Hydrogenosomes -- Hydrogenosomes of Anaerobic Chytrids: An Alternative Way to Adapt to Anaerobic Environments -- The Proteome of T. vaginalis Hydrogenosomes -- Hydrogenosome: The Site of 5-Nitroimidazole Activation and Resistance -- Mitosomes in Parasitic Protists -- The Mitochondrion-Related Organelle of Cryptosporidium parvum -- Mitochondrial Remnant in Blastocystis -- Possible Mitochondria-Related Organelles in Poorly-Studied “Amitochondriate” Eukaryotes.
520			_a"Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes" provides a summary of the current knowledge of these organelles, which occur in unicellular, often parasitic organisms, including human pathogens. The distribution of these organelles is broad, but they were detected primarily in an anoxic habitat or nutrient rich intracellular niche that permits life without the efficient energy generating system of typical mitochondria. Their common characteristic is that they lack the aerobic energy conservation system of typical mitochondria and that they are usually the site of the synthesis of iron-sulfur clusters, regarded as the only indispensable function of eukaryotic mitochondria. These mitochondria-related organelles exhibit a variety of structures and functions. This work describes properties such as protein import, structure, metabolism, adaptation, proteome and their role in drug activation and resistance. Further topics include the evolution and biogenesis of these organelles.
650		0	_aLife sciences.
650		0	_aBiochemistry.
650		0	_aCell biology.
650		0	_aEvolutionary biology.
650		0	_aMicrobiology.
650	1	4	_aLife Sciences.
650	2	4	_aCell Biology.
650	2	4	_aEukaryotic Microbiology.
650	2	4	_aBiochemistry, general.
650	2	4	_aEvolutionary Biology.
700	1		_aTachezy, Jan. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540767329
830		0	_aMicrobiology Monographs, _x1862-5576 ; _v9
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-540-76733-6
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c504128 _d504128