000 | 02687nam a22004815i 4500 | ||
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001 | 978-3-540-76330-7 | ||
003 | DE-He213 | ||
005 | 20161121230810.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2008 gw | s |||| 0|eng d | ||
020 |
_a9783540763307 _9978-3-540-76330-7 |
||
024 | 7 |
_a10.1007/978-3-540-76330-7 _2doi |
|
050 | 4 | _aRC321-580 | |
072 | 7 |
_aPSAN _2bicssc |
|
072 | 7 |
_aMED057000 _2bisacsh |
|
082 | 0 | 4 |
_a612.8 _223 |
245 | 1 | 0 |
_aSynaptic Plasticity and the Mechanism of Alzheimer's Disease _h[electronic resource] / _cedited by Dennis J. Selkoe, Antoine Triller, Yves Christen. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008. |
|
300 |
_aXII, 183 p. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
||
337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
||
347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aResearch and Perspectives in Alzheimer's Disease, _x0945-6066 |
|
505 | 0 | _aPermanence of the Synapse and Molecular Instability -- Cellular Biology of AMPA Receptor Trafficking and Synaptic Plasticity -- Imaging of Experience-Dependent Structural Plasticity in the Mouse Neocortex in vivo -- Synapse Loss, Synaptic Plasticity and the Postsynaptic Density -- Impact of Beta Amyloid on Excitatory Synaptic Transmission and Plasticity -- Quantitative Neuropathology in Alzheimer’s Mouse Models -- Multiple Levels of Synaptic Regulation by NMDA-type Glutamate Receptor in Normal and Disease States -- Soluble Oligomers of the Amyloid ?-Protein: Impair Synaptic Plasticity and Behavior -- Why Alzheimer’s is a Disease of Memory: Synaptic Targeting by Pathogenic A? Oligomers (ADDLs) -- Synaptic Transmission Dynamically Modulates Interstitial Fluid Amyloid-? Levels -- A?-Induced Toxicity Mediated by Caspase Cleavage of the Amyloid Precursor Protein (APP) -- Long-Term Potentiation and A?: Targeting A? Species, Cellular Mechanisms and Putative Receptors -- Genes, Synapses and Autism Spectrum Disorders. | |
520 | _a(will follow). | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aHuman physiology. | |
650 | 0 | _aNeurosciences. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aNeurosciences. |
650 | 2 | 4 | _aHuman Physiology. |
700 | 1 |
_aSelkoe, Dennis J. _eeditor. |
|
700 | 1 |
_aTriller, Antoine. _eeditor. |
|
700 | 1 |
_aChristen, Yves. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540763291 |
830 | 0 |
_aResearch and Perspectives in Alzheimer's Disease, _x0945-6066 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-540-76330-7 |
912 | _aZDB-2-SBL | ||
950 | _aBiomedical and Life Sciences (Springer-11642) | ||
999 |
_c504127 _d504127 |