000 03561nam a22004815i 4500
001 978-3-540-75546-3
003 DE-He213
005 20161121230809.0
007 cr nn 008mamaa
008 100301s2008 gw | s |||| 0|eng d
020 _a9783540755463
_9978-3-540-75546-3
024 7 _a10.1007/978-3-540-75546-3
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aGroup B Coxsackieviruses
_h[electronic resource] /
_cedited by Steven Tracy, M. Steven Oberste, Kristen M. Drescher.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2008.
300 _aXIX, 340 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v323
505 0 _aCVB Genetics -- Coxsackieviruses and Quasispecies Theory: Evolution of Enteroviruses -- Comparative Genomics of the Coxsackie B Viruses and Related Enteroviruses -- Group B Coxsackievirus Virulence -- CVB Entry and Replication -- The Coxsackievirus and Adenovirus Receptor -- Coxsackievirus B RNA Replication: Lessons from Poliovirus -- CVB Translation: Lessons from the Polioviruses -- Preferential Coxsackievirus Replication in Proliferating/Activated Cells: Implications for Virus Tropism, Persistence, and Pathogenesis -- Host-Virus Interaction -- The Impact of CVB3 Infection on Host Cell Biology -- Host Immune Responses to Coxsackievirus B3 -- Pediatric Group B Coxsackievirus Infections -- CVB-Induced Pancreatitis and Alterations in Gene Expression -- The CVB and Etiology of Type 1 Diabetes -- Persistent Coxsackievirus Infection: Enterovirus Persistence in Chronic Myocarditis and Dilated Cardiomyopathy -- Autoimmunity in Coxsackievirus Infection -- CVB Infection and Mechanisms of Viral Cardiomyopathy.
520 _aThis monograph reviews information published since 1997 on the group B coxsackieviruses (CVB), a large and important group of human enteroviruses. The CVB were discovered in the mid-20th century, during the search for other poliovirus types, and within a very few years of this discovery, the CVB had been implicated as causes of human myocarditis and pancreatitis. The study of the CVB is still inextricably linked with the fate of their well-known relatives, the polioviruses, for as poliovirus eradication proceeds around the world, the CVB emerge more prominently as the enteroviruses best suited for continuing studies in enteroviral molecular biology as well as understanding the mechanisms underlying enteroviral pathogenesis. This volume reviews and presents modern views on the spectrum of CVB biologies, from interaction of the virus with its receptor through replication, speciation, and induction of disease.
650 0 _aMedicine.
650 0 _aMedical microbiology.
650 0 _aVirology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
650 2 4 _aMedical Microbiology.
700 1 _aTracy, Steven.
_eeditor.
700 1 _aOberste, M. Steven.
_eeditor.
700 1 _aDrescher, Kristen M.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540755456
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v323
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-75546-3
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c504118
_d504118