000 | 03150nam a22004575i 4500 | ||
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001 | 978-3-540-73900-5 | ||
003 | DE-He213 | ||
005 | 20161121230808.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2008 gw | s |||| 0|eng d | ||
020 |
_a9783540739005 _9978-3-540-73900-5 |
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024 | 7 |
_a10.1007/978-3-540-73900-5 _2doi |
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050 | 4 | _aQR180-189.5 | |
072 | 7 |
_aMJCM _2bicssc |
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072 | 7 |
_aMED044000 _2bisacsh |
|
082 | 0 | 4 |
_a616.079 _223 |
245 | 1 | 0 |
_aSpecialization and Complementation of Humoral Immune Responses to Infection _h[electronic resource] / _cedited by Tim Manser. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008. |
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300 |
_aXII, 162 p. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v319 |
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505 | 0 | _aPattern Recognition by B Cells: The Role of Antigen Repetitiveness Versus Toll-Like Receptors -- The Multifunctional Role of Antibodies in the Protective Response to Bacterial T Cell-Independent Antigens -- B Cell Lineage Contributions to Antiviral Host Responses -- The Important and Diverse Roles of Antibodies in the Host Response to Borrelia Infections -- A Distinct Role for B1b Lymphocytes in T Cell-Independent Immunity -- Secretory Immunity Following Mutans Streptococcal Infection or Immunization. | |
520 | _aIn recent years the results of past studies on T cell dependent and T cell independent antibody responses have coalesced with discoveries regarding the roles of various primary B cell subsets and components of the innate immune system in conferring resistance to infectious pathogens. As a consequence, a new and more complete understanding of how antibody-mediated resistance to pathogens is elaborated has emerged. The recent explosion of knowledge of Toll-like receptor specificity and function has further embellished this understanding. It is now clear that there is not only extensive overlap and cross-complementarity in the action of innate and adaptive immune systems, but also specialization of function of the various B cell subsets and the types of antibodies they produce. This synergistic interaction of multiple components of these systems is perhaps best exemplified in antibody responses to bacteria. Contributions to this monograph were chosen to highlight this new perspective on antibody responses to infection, as well as to convey its practical implications, such as for contemporary vaccine design. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aImmunology. | |
650 | 0 | _aVirology. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aImmunology. |
650 | 2 | 4 | _aVirology. |
700 | 1 |
_aManser, Tim. _eeditor. |
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710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540738992 |
830 | 0 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v319 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-540-73900-5 |
912 | _aZDB-2-SBL | ||
950 | _aBiomedical and Life Sciences (Springer-11642) | ||
999 |
_c504095 _d504095 |