000 03150nam a22004575i 4500
001 978-3-540-73900-5
003 DE-He213
005 20161121230808.0
007 cr nn 008mamaa
008 100301s2008 gw | s |||| 0|eng d
020 _a9783540739005
_9978-3-540-73900-5
024 7 _a10.1007/978-3-540-73900-5
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
245 1 0 _aSpecialization and Complementation of Humoral Immune Responses to Infection
_h[electronic resource] /
_cedited by Tim Manser.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2008.
300 _aXII, 162 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v319
505 0 _aPattern Recognition by B Cells: The Role of Antigen Repetitiveness Versus Toll-Like Receptors -- The Multifunctional Role of Antibodies in the Protective Response to Bacterial T Cell-Independent Antigens -- B Cell Lineage Contributions to Antiviral Host Responses -- The Important and Diverse Roles of Antibodies in the Host Response to Borrelia Infections -- A Distinct Role for B1b Lymphocytes in T Cell-Independent Immunity -- Secretory Immunity Following Mutans Streptococcal Infection or Immunization.
520 _aIn recent years the results of past studies on T cell dependent and T cell independent antibody responses have coalesced with discoveries regarding the roles of various primary B cell subsets and components of the innate immune system in conferring resistance to infectious pathogens. As a consequence, a new and more complete understanding of how antibody-mediated resistance to pathogens is elaborated has emerged. The recent explosion of knowledge of Toll-like receptor specificity and function has further embellished this understanding. It is now clear that there is not only extensive overlap and cross-complementarity in the action of innate and adaptive immune systems, but also specialization of function of the various B cell subsets and the types of antibodies they produce. This synergistic interaction of multiple components of these systems is perhaps best exemplified in antibody responses to bacteria. Contributions to this monograph were chosen to highlight this new perspective on antibody responses to infection, as well as to convey its practical implications, such as for contemporary vaccine design.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aVirology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aVirology.
700 1 _aManser, Tim.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540738992
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v319
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-73900-5
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c504095
_d504095