000			03175nam a22005415i 4500
001			978-3-540-72718-7
003			DE-He213
005			20161121230807.0
007			cr nn 008mamaa
008			100301s2008 gw | s |||| 0|eng d
020			_a9783540727187 _9978-3-540-72718-7
024	7		_a10.1007/978-3-540-72718-7 _2doi
050		4	_aRM1-950
072		7	_aMMG _2bicssc
072		7	_aMED071000 _2bisacsh
082	0	4	_a615 _223
245	1	0	_aMolecular Imaging I _h[electronic resource] / _cedited by Wolfhard Semmler, Markus Schwaiger.
246	3		_aWith contributions by numerous experts
264		1	_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2008.
300			_aXXVII, 280 p. 132 illus., 51 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aHandbook of Experimental Pharmacology, _x0171-2004 ; _v185/1
505	0		_aInstrumentation -- Fundamentals of Optical Imaging -- Micro-CT -- PET & SPECT Instrumentation -- Magnetic Resonance Imaging and Spectroscopy -- Ultrasound Basics -- Multimodal Imaging Approaches: PET/CT and PET/MRI -- Imaging Probes -- Contrast Agents: Magnetic Resonance -- Contrast Agents: X-ray Contrast Agents and Molecular Imaging – A Contradiction? -- Radiopharmaceuticals: Molecular Imaging using Positron Emission Tomography -- Optical Agents -- Ultrasound Contrast Agents for Molecular Imaging -- Agents for Polarization Enhancement in MRI.
520			_aThe aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is being addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.
650		0	_aMedicine.
650		0	_aPharmacology.
650		0	_aRadiology.
650		0	_aNuclear medicine.
650		0	_aRadiotherapy.
650	1	4	_aBiomedicine.
650	2	4	_aPharmacology/Toxicology.
650	2	4	_aImaging / Radiology.
650	2	4	_aNuclear Medicine.
650	2	4	_aUltrasound.
650	2	4	_aRadiotherapy.
700	1		_aSemmler, Wolfhard. _eeditor.
700	1		_aSchwaiger, Markus. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9783540727170
830		0	_aHandbook of Experimental Pharmacology, _x0171-2004 ; _v185/1
856	4	0	_uhttp://dx.doi.org/10.1007/978-3-540-72718-7
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c504075 _d504075