000 03367nam a22004575i 4500
001 978-3-540-70995-4
003 DE-He213
005 20161121230807.0
007 cr nn 008mamaa
008 100301s2008 gw | s |||| 0|eng d
020 _a9783540709954
_9978-3-540-70995-4
024 7 _a10.1007/978-3-540-70995-4
_2doi
050 4 _aRM1-950
072 7 _aMMG
_2bicssc
072 7 _aMED071000
_2bisacsh
082 0 4 _a615
_223
245 1 0 _aDrug Discovery and Evaluation
_h[electronic resource] :
_bPharmacological Assays /
_cedited by Hans Gerhard Vogel.
250 _aThird Completely Revised, Updated and Enlarged Edition.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg :
_bImprint: Springer,
_c2008.
300 _aeReference.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
520 _aThe rapid progress in biology will continue to change the methodological approach to drug discovery in the coming years. Electronic media will continuously help researchers to access and share information. It is, however, becoming more and more evident that many young pharmacologists have only limited training in classical pharmacological methodologies. These long-standing and still highly relevant methods are simply not available in the electronic databases. Drug Discovery and Evaluation:Pharmacological Assays bridges this gap by comprehensively covering the pharmacological methods that have been utilized successfully for more than a hundred years as well as the latest technologies. The classical methods and the newest technologies, all in one book! The 3rd edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the more than 1000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this third edition, all existing chapters have been revised and completely updated. A large number of assays were added: we are now publishing two volumes. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis (formerly called activity of blood constituents), - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. Audience: Pharmacologists and Pharmacists in Academia and Industry.
650 0 _aMedicine.
650 0 _aPharmacy.
650 0 _aPharmacology.
650 0 _aBiochemistry.
650 1 4 _aBiomedicine.
650 2 4 _aPharmacology/Toxicology.
650 2 4 _aPharmacy.
650 2 4 _aBiochemistry, general.
700 1 _aVogel, Hans Gerhard.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540714200
856 4 0 _uhttp://dx.doi.org/10.1007/978-3-540-70995-4
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c504051
_d504051