000 03720nam a22005055i 4500
001 978-1-59745-199-4
003 DE-He213
005 20161121230803.0
007 cr nn 008mamaa
008 100301s2007 xxu| s |||| 0|eng d
020 _a9781597451994
_9978-1-59745-199-4
024 7 _a10.1007/978-1-59745-199-4
_2doi
050 4 _aQH573-671
072 7 _aPSF
_2bicssc
072 7 _aSCI049000
_2bisacsh
082 0 4 _a571.6
_223
245 1 0 _aApoptosis, Cell Signaling, and Human Diseases
_h[electronic resource] :
_bMolecular Mechanisms, Volume 2 /
_cedited by Rakesh Srivastava.
264 1 _aTotowa, NJ :
_bHumana Press,
_c2007.
300 _aXVI, 402 p. 49 illus., 1 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aKinases and Phosphatases -- Significance of Protein Kinase A in Cancer -- Protein Kinase C and Apoptosis -- The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infection -- Cyclin-Dependent Kinase 5 -- Critical Roles of the Raf/MEK/ERK Pathway in Apoptosis and Drug Resistance -- MAPK Signaling in Human Diseases -- Serine/Threonine Protein Phosphatases in Apoptosis -- Urokinase/Urokinase Receptor-Mediated Signaling in Cancer -- Molecular Basis of Cell Death -- Signaling Pathways That Protect the Heart Against Apoptosis Induced by Ischemia and Reperfusion -- Cyclooxygenase-2 Gene Expression -- Death Receptors -- DNA Damage-Dependent Apoptosis -- The Role of Proteasome in Apoptosis -- Apoptosis Induction in T Lymphocytes by HIV -- Inhibitor of Apoptosis Proteins and Caspases -- Intracellular Pathways Involved in DNA Damage and Repair to Neuronal Apoptosis -- The Biology of Caspases -- Apoptosis and Human Diseases: Molecular Mechanisms.
520 _aApoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 & 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer and neurodegenerative diseases. These comprehensive volumes integrate the most innovative and current findings from several related disciplines of scientific research, including pathology, genetics, virology, cell biology, immunology, and molecular biology. Volume 1 is divided into two sections: "Malignant Transformation and Metastasis" and "Molecular Basis of Disease Therapy." Volume 2 follows a similar structure and is divided into sections entitled "Kinases and Phosphate" and "Molecular Basis of Cell Death." All of the contributors are at the forefront of scientific discovery, and the reviews they present systemically examine the most exciting and innovative aspects of their particular areas of expertise. Researchers will find these volumes of major benefit as they search for novel and more effective treatments for human diseases.
650 0 _aLife sciences.
650 0 _aInfectious diseases.
650 0 _aBiochemistry.
650 0 _aCell biology.
650 0 _aDevelopmental biology.
650 0 _aMicrobiology.
650 1 4 _aLife Sciences.
650 2 4 _aCell Biology.
650 2 4 _aBiochemistry, general.
650 2 4 _aDevelopmental Biology.
650 2 4 _aMicrobiology.
650 2 4 _aInfectious Diseases.
700 1 _aSrivastava, Rakesh.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9781588298829
856 4 0 _uhttp://dx.doi.org/10.1007/978-1-59745-199-4
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503956
_d503956