000			03679nam a22004455i 4500
001			978-1-59745-147-5
003			DE-He213
005			20161121230803.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9781597451475 _9978-1-59745-147-5
024	7		_a10.1007/978-1-59745-147-5 _2doi
050		4	_aRC321-580
072		7	_aPSAN _2bicssc
072		7	_aMED057000 _2bisacsh
082	0	4	_a612.8 _223
245	1	0	_aCell Therapy, Stem Cells, and Brain Repair _h[electronic resource] / _cedited by Cyndy Davis Sanberg, Paul R. Sanberg.
264		1	_aTotowa, NJ : _bHumana Press, _c2007.
300			_bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aContemporary Neuroscience
505	0		_aCurrent Views of the Embryonic and Neural Stem Cell -- Developing Novel Cell Sources for Transplantation in Parkinson’s Disease -- Neural Transplantation in the Nonhuman Primate Model of Parkinson’s Disease -- Cell-Based Therapy for Huntington’s Disease -- Use of Bone Marrow Stem Cells as Therapy for Behavioral Deficits in Rodent Models of Huntington’s Disease -- Human Neuroteratocarcinoma Cells as a Neural Progenitor Graft Source for Cell Transplantation in Stroke -- Therapeutic Applications of Bone Marrow-Derived Stem Cells in Neurologic Injury and Disease -- Cell Therapy for Models of Pain and Traumatic Brain Injury -- The Use of Sertoli Cells in Neural Transplantation -- The Choroid Plexus -- Progress and Challenges in Immunoisolation for CNS Cell Therapy -- Evidence-Based Methodology for Advancing Neural Reconstruction -- Hematopoietic Cell Therapy for Brain Repair -- Stem Cells and Regenerative Medicine.
520			_aAs our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body’s own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases.
650		0	_aMedicine.
650		0	_aNeurosciences.
650	1	4	_aBiomedicine.
650	2	4	_aNeurosciences.
700	1		_aSanberg, Cyndy Davis. _eeditor.
700	1		_aSanberg, Paul R. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588295026
830		0	_aContemporary Neuroscience
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-59745-147-5
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c503953 _d503953