000 03805nam a22004455i 4500
001 978-0-387-78225-6
003 DE-He213
005 20161121230753.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387782256
_9978-0-387-78225-6
024 7 _a10.1007/978-0-387-78225-6
_2doi
050 4 _aTP248.6
072 7 _aTCBG
_2bicssc
072 7 _aSCI029000
_2bisacsh
082 0 4 _a660.65
_223
245 1 0 _aTransgenesis and the Management of Vector-Borne Disease
_h[electronic resource] /
_cedited by Serap Aksoy.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _aXVIII, 171 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v627
505 0 _aPerspectives on the State of Insect Transgenics -- Alphavirus Transducing Systems -- Paratransgenesis Applied for Control of Tsetse Transmitted Sleeping Sickness -- Bacteria of the Genus Asaia: A Potential Paratransgenic Weapon Against Malaria -- Proposed Uses of Transposons in Insect and Medical Biotechnology -- The Yin and Yang of Linkage Disequilibrium: Mapping of Genes and Nucleotides Conferring Insecticide Resistance in Insect Disease Vectors -- Impact of Technological Improvements on Traditional Control Strategies -- Insect Population Suppression Using Engineered Insects -- Wolbachia- Based Technologies for Insect Pest Population Control -- Using Predictive Models to Optimize Wolbachia-Based Strategies for Vector-Borne Disease Control -- Modifying Insect Population Age Structure to Control Vector-Borne Disease -- Technological Advances to Enhance Agricultural Pest Management -- Applications of Mosquito Ecology for Successful Insect Transgenesis-Based Disease Prevention Programs.
520 _aParasitic, bacterial and viral agents continue to challenge the welfare of humans, livestock, wild life and plants worldwide. The public health impact and financial consequences of these diseases are particularly hard on the already overburdened economies of developing countries especially in the tropics. Many of these disease agents utilize insect hosts (vectors) to achieve their transmission to mammals. In the past, these diseases were largely controlled by insecticide-based vector reduction strategies. Now, many of these diseases have reemerged in the tropics, recolonizing their previous range, and expanding into new territories previously not considered to be endemic. Habitat change, irrigation practices, atmospheric and climate change, insecticide and drug resistance as well as increases in global tourism, human traffic and commercial activities, have driven the reemergence and spread of vector borne diseases. While these diseases can be controlled through interventions aimed at both their vertebrate and invertebrate hosts, no effective vaccines exist, and only limited therapeutic prospects are available for their control in mammalian hosts. Molecular technologies such as transgenesis, which is the subject of this book, stand to increase the toolbox and benefit disease management strategies.
650 0 _aChemistry.
650 0 _aGenetic engineering.
650 1 4 _aChemistry.
650 2 4 _aGenetic Engineering.
650 2 4 _aBiomedicine general.
700 1 _aAksoy, Serap.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387782249
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v627
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-78225-6
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503718
_d503718