000 03201nam a22004935i 4500
001 978-0-387-74021-8
003 DE-He213
005 20161121230751.0
007 cr nn 008mamaa
008 100301s2007 xxu| s |||| 0|eng d
020 _a9780387740218
_9978-0-387-74021-8
024 7 _a10.1007/978-0-387-74021-8
_2doi
050 4 _aQR1-502
072 7 _aPSG
_2bicssc
072 7 _aSCI045000
_2bisacsh
082 0 4 _a579
_223
245 1 0 _aEukaryotic Membranes and Cytoskeleton
_h[electronic resource] :
_bOrigins and Evolution.
264 1 _aNew York, NY :
_bSpringer New York,
_c2007.
300 _aXV, 145 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v607
505 0 _aThe Early Eukaryotic Fossil Record -- The Diversity Of Eukaryotes And The Root Of The Eukaryotic Tree -- Origin of Eukaryotic Endomembranes: A Critical Evaluation of Different Model Scenarios -- Origins and Evolution of Cotranslational Transport to the ER -- Evolution of the Endoplasmic Reticulum and the Golgi Complex -- An Evolutionary Perspective on Eukaryotic Membrane Trafficking -- Reconstructing the Evolution of the Endocytic System: Insights from Genomics and Molecular Cell Biology -- Origins and Evolution of the Actin Cytoskeleton -- Origin and Evolution of Self-Consumption: Autophagy -- Origin and Evolution of the Centrosome -- The Evolution of Eukaryotic Cilia and Flagella as Motile and Sensory Organelles.
520 _aEukaryotic Membranes and Cytoskeleton: Origins and Evolution discusses the evolutionary origin and diversification of eukaryotic endomembranes and cytoskeleton from a cell biological and comparative genomic perspective. Many of the chapters present original research data from comparative genomic surveys. The presence/absence of gene families with central roles in endomembrane and cytoskeleton dynamics in a variety of eukaryotic taxa and an understanding of eukaryote phylogeny allow us to accurately reconstruct the cellular machineries present in the last common ancestor of eukaryotes. Such a reconstruction is fundamental if we are to understand eukaryotic diversification since this is the ancestral cell from which all diversity arose. Comparative genomics can likewise tell us which lineages expanded or reduced certain gene families and the associated cellular machineries.
650 0 _aLife sciences.
650 0 _aHuman genetics.
650 0 _aCell biology.
650 0 _aEvolutionary biology.
650 0 _aMicrobiology.
650 1 4 _aLife Sciences.
650 2 4 _aEukaryotic Microbiology.
650 2 4 _aCell Biology.
650 2 4 _aEvolutionary Biology.
650 2 4 _aHuman Genetics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387740201
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v607
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-74021-8
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503682
_d503682