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001 978-0-387-73364-7
003 DE-He213
005 20161121230751.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387733647
_9978-0-387-73364-7
024 7 _a10.1007/978-0-387-73364-7
_2doi
050 4 _aQP351-495
072 7 _aPSAN
_2bicssc
072 7 _aSCI070000
_2bisacsh
072 7 _aMED057000
_2bisacsh
082 0 4 _a573.8
_223
245 1 0 _aHair Cell Regeneration, Repair, and Protection
_h[electronic resource] /
_cedited by Richard J. Salvi, Arthur N. Popper, Richard R. Fay.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Handbook of Auditory Research,
_x0947-2657 ;
_v33
505 0 _aOverview: Regeneration and Repair -- Morphological Correlates of Regeneration and Repair in the Inner Ear -- Recovery of Function in the Avian Auditory System After Ototrauma -- Functional Recovery After Hair Cell Regeneration in Birds -- Hair Cell Regeneration: Mechanisms Guiding Cellular Proliferation and Differentiation -- Protection and Repair of Inner Ear Sensory Cells -- Gene Arrays, Cell Lines, Stem Cells, and Sensory Regeneration in Mammalian Ears.
520 _aThe sensory hair cells in the inner ear and vestibular system convert mechanical stimuli, sound and motion into neural activity that is responsible for the sensations of hearing, motion and head position. In mammals, the loss of hair cells from acoustic overstimulation, ototoxic drugs and aging is irreversible, leading to a permanent loss of function. However, it is now clear that hair cells in other vertebrates are capable of regenerating and recovering partial or complete function. Moreover, partially damaged hair cells can undergo self-repair or be protected from traumatic insults by external compounds. Hair Cell Regeneration, Repair, and Protection provides a comprehensive survey of what is currently known about the regeneration, repair and protection of sensory hair cells and subsequent recovery of function in the auditory and vestibular system. The aim is to provide graduate students, postdoctoral fellows, clinicians and scientists in related disciplines with the biological bases of hair cells and with an understanding of the factors that contribute to their regeneration and repair. Table of Contents: Overview: Regeneration and repair Richard J. Salvi Morphological Correlates of Regeneration and Repair in the Inner Ear Jason R. Meyers and Jeffrey T. Corwin The recovery of function in the avian auditory system following ototrauma James C. Saunders and Richard J. Salvi Functional recovery following hair cell regeneration in birds Robert J. Dooling, Micheal L. Dent, Amanda M. Lauer, and Brenda M. Ryals Hair cell regeneration: Mechanisms guiding cellular proliferation and differentiation Elizabeth C. Oesterle and Jennifer S. Stone Protection and repair of inner ear sensory cells Andrew Forge and Thomas R. Van De Water Gene arrays, cell lines, stem cells, and sensory regeneration in mammalian ears Marcelo N. Rivolta and Matthew C. Holley About the editors: Richard J. Salvi, Center for Hearing and Deafness, University of Buffalo, NY. Arthur N. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Richard R. Fay is Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago.
650 0 _aLife sciences.
650 0 _aHuman physiology.
650 0 _aNeurosciences.
650 0 _aNeurobiology.
650 1 4 _aLife Sciences.
650 2 4 _aNeurobiology.
650 2 4 _aHuman Physiology.
650 2 4 _aNeurosciences.
700 1 _aSalvi, Richard J.
_eeditor.
700 1 _aPopper, Arthur N.
_eeditor.
700 1 _aFay, Richard R.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387733630
830 0 _aSpringer Handbook of Auditory Research,
_x0947-2657 ;
_v33
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-73364-7
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503673
_d503673