000 | 03482nam a22004095i 4500 | ||
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001 | 978-0-387-68561-8 | ||
003 | DE-He213 | ||
005 | 20161121230748.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2007 xxu| s |||| 0|eng d | ||
020 |
_a9780387685618 _9978-0-387-68561-8 |
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024 | 7 |
_a10.1007/978-0-387-68561-8 _2doi |
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050 | 4 | _aRC321-580 | |
072 | 7 |
_aPSAN _2bicssc |
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072 | 7 |
_aMED057000 _2bisacsh |
|
082 | 0 | 4 |
_a612.8 _223 |
245 | 1 | 0 |
_aIntracellular Mechanisms for Neuritogenesis _h[electronic resource] / _cedited by Ivan de Curtis. |
264 | 1 |
_aBoston, MA : _bSpringer US, _c2007. |
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300 |
_aXV, 333 p. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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505 | 0 | _aAdhesion-Induced Intracellular Mechanisms of Neurite Elongation -- Regulation of Growth Cone Initiation and Actin Dynamics by ADF/Cofilin -- Role of Microtubules and MAPs During Neuritogenesis -- Small GTPases: Mechanisms Linking Membrane Traffic to Cytoskeleton During Neuritogenesis -- Exocytic Mechanisms for Axonal and Dendritic Growth -- Role of the Golgi Apparatus During Axon Formation -- Focal Adhesion Kinase in Neuritogenesis -- Regulation of Neuronal Morphogenesis by Abl Family Kinases -- Membrane Glycolipids in Neurotrophin Receptor-Mediated Signaling -- Wnt Signaling in Neurite Development -- Role of CRMP-2 in Neuronal Polarization -- Regulation of Axon Branching -- Comparative Analysis of Neural Crest Cell and Axonal Growth Cone Dynamics and Behavior -- Mechanisms of Axon Regeneration. | |
520 | _aA major issue of modern neurobiology is to understand how neurons extend their neurites to form a functional network. While a large amount of information is available on the extracellular mechanisms driving neuritogenesis, the study of the intricate molecular machinery underlying the intracellular mechanisms has only recently been addressed. The purpose of this book is to present novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction. In particular, the proposed authors would address the importance of the integration among distinct aspects of the cell biology of developing neurons involved in neurite extension. The aim of the book is to present this topic to the general readership of neurobiologists and molecular and cellular biologists to further stimulate the interest into this exciting section of neurobiology. Moreover, the book could represent a reference for researchers directly involved in the study of neuronal development, and a textbook for PhD courses in molecular neurobiology The authors contributing to this book are all internationally recognized leaders in their respective fields of research, and the work from their laboratories embodies state of the art approaches to address this fundamental aspect of molecular neurobiology. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aNeurosciences. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aNeurosciences. |
700 | 1 |
_aCurtis, Ivan de. _eeditor. |
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710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9780387331287 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-0-387-68561-8 |
912 | _aZDB-2-SBL | ||
950 | _aBiomedical and Life Sciences (Springer-11642) | ||
999 |
_c503607 _d503607 |