000 03772nam a22005535i 4500
001 978-0-387-35966-3
003 DE-He213
005 20161121230747.0
007 cr nn 008mamaa
008 120814s2007 xxu| s |||| 0|eng d
020 _a9780387359663
_9978-0-387-35966-3
024 7 _a10.1007/978-0-387-35966-3
_2doi
050 4 _aQH505
072 7 _aPHVN
_2bicssc
072 7 _aPHVD
_2bicssc
072 7 _aSCI009000
_2bisacsh
082 0 4 _a571.4
_223
245 1 0 _aProtein Interactions
_h[electronic resource] :
_bBiophysical Approaches for the Study of Complex Reversible Systems /
_cedited by Peter Schuck.
264 1 _aBoston, MA :
_bSpringer US :
_bImprint: Springer,
_c2007.
300 _aXI, 532 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aProtein Reviews ;
_v5
505 0 _aThe Characterization of Biomolecular Interactions Using Fluorescence Fluctuation Techniques -- Characterization of Protein–Protein Interactions Using Atomic Force Microscopy -- Combined Solid-Phase Detection Techniques for Dissecting Multiprotein Interactions on Membranes -- Surface Plasmon Resonance Biosensing in the Study of Ternary Systems of Interacting Proteins -- Mass Spectrometry for Studying Protein Modifications and for Discovery of Protein Interactions -- H/2H Exchange Mass Spectrometry of Protein Complexes -- Elucidation of Protein–Protein and Protein–Ligand Interactions by NMR Spectroscopy -- Application of Isothermal Titration Calorimetry in Exploring the Extended Interface -- Solvent Mediated Protein–Protein Interactions -- Sedimentation Equilibrium Analytical Ultracentrifugation for Multicomponent Protein Interactions -- Structure Analysis of Macromolecular Complexes by Solution Small-Angle Scattering -- Fluorescence Detection of Proximity -- Steady-State and Time-Resolved Emission Anisotropy -- Analysis of Protein-DNA Equilibria by Native Gel Electrophoresis -- Electrospray Ionization Mass Spectrometry and the Study of Protein Complexes -- Sedimentation Velocity in the Study of Reversible Multiprotein Complexes.
520 _aThis comprehensive volume, written by experts in the field, brings together a coherent set of reviews of different biophysical methodologies for the study of reversible protein interactions. These reviews allow the reader to gain a deep understanding of the biophysical observables, to stimulate creative thought on how the techniques may be applied to study a particular biological system, and to foster collaboration and multi-disciplinary work. The side-by-side presentation of different approaches highlights aspects they have in common, as well as orthogonal viewpoints that may provide opportunities for synergistic combination. Protein Interactions is an ideal book for biochemists, protein scientists, bioenginners, and molecular and cellular biologists.
650 0 _aPhysics.
650 0 _aAnalytical chemistry.
650 0 _aMedical biochemistry.
650 0 _aBiochemistry.
650 0 _aCell biology.
650 0 _aBiophysics.
650 0 _aBiological physics.
650 1 4 _aPhysics.
650 2 4 _aBiophysics and Biological Physics.
650 2 4 _aMedical Biochemistry.
650 2 4 _aCell Biology.
650 2 4 _aBiochemistry, general.
650 2 4 _aAnalytical Chemistry.
700 1 _aSchuck, Peter.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387359656
830 0 _aProtein Reviews ;
_v5
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-35966-3
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503566
_d503566