000 03078nam a22005535i 4500
001 978-0-387-34127-9
003 DE-He213
005 20161121230746.0
007 cr nn 008mamaa
008 100301s2007 xxu| s |||| 0|eng d
020 _a9780387341279
_9978-0-387-34127-9
024 7 _a10.1007/978-0-387-34127-9
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aLatency Strategies of Herpesviruses
_h[electronic resource] /
_cedited by Janos Minarovits, Eva Gonczol, Tibor Valyi-Nagy.
264 1 _aBoston, MA :
_bSpringer US,
_c2007.
300 _aXII, 300 p. 19 illus., 3 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aLatency Strategies of Alphaherpesviruses: Herpes Simplex Virus and Varicella-Zoster Virus Latency in Neurons -- Modulation of Apoptotic Pathways by Herpes Simplex Viruses -- Cytomegalovirus Latency -- Human Herpesvirus 6 and Human Herpesvirus 7 -- Murid Herpesvirus 4 (MuHV-4): An Animal Model for Human Gammaherpesvirus Research -- Latency Strategies of Equine Herpesviruses -- The Multifunctional Latency-Associated Nuclear Antigen of Kaposi's Sarcoma-Associated Herpesvirus -- Epstein-Barr Virus.
520 _aLatency is a fascinating property of herpesviruses which ensures the maintenance of their genetic information in their hosts for an extended period in the absence of productive virus replication. Focusing on human herpesviruses and animal models of herpesvirus-associated human diseases, this is the first book dealing with the intricate epigenetic mechanisms (DNA methylation, histone modification, alteration of chromatin structure) that regulate latency-associated transcription. Special attention is given to immune evasion "tricks" blocking immune responses to herpesvirus infected cells and viral RNAs and proteins involved in malignant transformation. Latency Strategies of Herpesviruses is an ideal book for researchers, scientists and graduate students in the fields of virology, immunology, microbiology, bacteriology, and veterinary medicine.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aVirology.
650 0 _aVeterinary medicine.
650 0 _aMicrobiology.
650 0 _aBacteriology.
650 0 _aAnimal genetics.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
650 2 4 _aImmunology.
650 2 4 _aMicrobiology.
650 2 4 _aBacteriology.
650 2 4 _aVeterinary Medicine.
650 2 4 _aAnimal Genetics and Genomics.
700 1 _aMinarovits, Janos.
_eeditor.
700 1 _aGonczol, Eva.
_eeditor.
700 1 _aValyi-Nagy, Tibor.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387324647
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-34127-9
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503555
_d503555