000			03658nam a22004335i 4500
001			978-0-387-32671-9
003			DE-He213
005			20161121230746.0
007			cr nn 008mamaa
008			100301s2008 xxu| s |||| 0|eng d
020			_a9780387326719 _9978-0-387-32671-9
024	7		_a10.1007/978-0-387-32671-9 _2doi
050		4	_aRC321-580
072		7	_aPSAN _2bicssc
072		7	_aMED057000 _2bisacsh
082	0	4	_a612.8 _223
245	1	0	_aHandbook of Neurochemistry and Molecular Neurobiology _h[electronic resource] : _bDevelopment and Aging Changes in the Nervous System / _cedited by Abel Lajtha, J. Regino Perez-Polo, Steffen Rossner.
264		1	_aBoston, MA : _bSpringer US, _c2008.
300			_aX, 324 p. 48 illus. eReference. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aNEUROTROPHINS AND CENTRAL NERVOUS SYSTEM DEVELOPMENT – D. B. Pereira and M. V. Chao -- NERVE GROWTH FACTOR REGULATED GENE EXPRESSION – L. A. Greene and J. M. Angelastro -- MYELINATING CELLS IN THE CENTRAL NERVOUS SYSTEM—DEVELOPMENT, AGING, AND DISEASE – J. Neman and J. de Vellis -- SULFUR-CONTAINING AMINO ACIDS IN THE CNS: HOMOCYSTEINE – D. K. Rassin -- STRESS RESPONSE SIGNAL TRANSDUCTION – X. Hu and J. R. Perez-Polo -- AGING AND OXIDATIVE STRESS RESPONSE IN THE CNS – V. Calabrese, D. A. Butterfield, and A. M. G. Stella -- PARALLELS BETWEEN NEURODEVELOPMENT AND NEURODEGENERATION: A CASE STUDY OF ALZHEIMER’S DISEASE – X. Zhu, G. Casadesus, K. M. Webber, C. S. Atwood, R. L. Bowen, G. Perry, and M. A. Smith -- DIFFERENTIATION AND DE-DIFFERENTIATION—NEURONAL CELL-CYCLE REGULATION DURING DEVELOPMENT AND AGE-RELATED NEURODEGENERATIVE DISORDERS – T. Arendt -- mRNA MODULATIONS IN STRESS AND AGING – E. Meshorer and H. Soreq -- MOLECULAR MECHANISMS OF DENDRITIC SPINE PLASTICITY IN DEVELOPMENT AND AGING – M. R. Kreutz, I. König, M. Mikhaylova, C. Spilker, and W. Zuschratter -- ALZHEIMER’S DISEASE BACE PROTEASES – S. Roßner and S. F. Lichtenthaler -- PROTEIN MISFOLDING, A COMMON MECHANISM IN THE PATHOGENESIS OF NEURODEGENERATIVE DISEASES – L. Vergara, K. Abid, and C. Soto -- ANTI-AGING STRATEGIES – J. A. Joseph and J. R. Perez-Polo.
520			_aIn the animal nervous system, a very high metabolic turnover, fragile but steep ionic gradients, and morphological and structural constraints - dictated by the necessity for prompt neuronal transmission of electrical impulses and necessary plasticity - result in a highly fragile organ system. Here, we address a small sampling of major constituents of neural function at the cellular and molecular level that play important roles in development and aging, two endogenous processes that embody features of allostasis or the dynamic shifts in set points for specific homeostatic mechanisms associated with development and aging. These chapters stress the dynamic features of neuronal responses to internal (developmental) cues or the more harmful external events (injury and disease) in a modern perspective.
650		0	_aMedicine.
650		0	_aNeurosciences.
650	1	4	_aBiomedicine.
650	2	4	_aNeurosciences.
700	1		_aLajtha, Abel. _eeditor.
700	1		_aPerez-Polo, J. Regino. _eeditor.
700	1		_aRossner, Steffen. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387326702
856	4	0	_uhttp://dx.doi.org/10.1007/978-0-387-32671-9
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c503546 _d503546