000 02903nam a22004575i 4500
001 978-0-387-09789-3
003 DE-He213
005 20161121230745.0
007 cr nn 008mamaa
008 100301s2008 xxu| s |||| 0|eng d
020 _a9780387097893
_9978-0-387-09789-3
024 7 _a10.1007/978-0-387-09789-3
_2doi
050 4 _aRC254-282
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a616.994
_223
245 1 0 _aMultichain Immune Recognition Receptor Signaling
_h[electronic resource] :
_bFrom Spatiotemporal Organization to Human Disease /
_cedited by Alexander B. Sigalov.
264 1 _aNew York, NY :
_bSpringer New York,
_c2008.
300 _aXXVII, 357 p. 70 illus., 3 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v640
505 0 _aMIRRs: Structure and Physiological Function -- T-Cell Receptor -- B-Cell Receptor -- Fc Receptors -- Natural Killer Cell Receptors -- Platelet Glycoprotein VI -- MIRR Signaling: Possible Mechanisms and the Techniques to Study and Visualize -- Clustering Models -- Segregation Models -- Kinetic Proofreading Model -- Serial Triggering Model -- Conformational Model -- Permissive Geometry Model -- Signaling Chain Homooligomerization (SCHOOL) Model -- Visualization of Cell-Cell Interaction Contacts-Synapses and Kinapses -- Visualization of Protein Interactions in Living Cells -- MIRR Signaling and Therapy of Immune Disorders -- Immunogenicity in Peptide-Immunotherapy: From Self/Nonself to Similar/Dissimilar Sequences -- Therapeutic Application of Transmembrane T and Natural Killer Cell Receptor Peptides -- Fc Receptor Targeting in the Treatment of Allergy, Autoimmune Diseases and Cancer -- Therapeutic Blockade of T- Cell Antigen Receptor Signal Transduction and Costimulation in Autoimmune Disease -- MHC and MHC-Like Molecules: Structural Perspectives on the Design of Molecular Vaccines -- SCHOOL Model and New Targeting Strategies -- Immune Receptor Signaling, Aging and Autoimmunity -- Viral Pathogenesis, Modulation of Immune Receptor Signaling and Treatment.
650 0 _aMedicine.
650 0 _aOncology.
650 0 _aLife sciences.
650 1 4 _aMedicine & Public Health.
650 2 4 _aOncology.
650 2 4 _aBiomedicine general.
650 2 4 _aLife Sciences, general.
700 1 _aSigalov, Alexander B.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387097886
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v640
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-09789-3
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c503533
_d503533