000 | 03344nam a22004455i 4500 | ||
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001 | 978-3-540-33990-8 | ||
003 | DE-He213 | ||
005 | 20161121230741.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2007 gw | s |||| 0|eng d | ||
020 |
_a9783540339908 _9978-3-540-33990-8 |
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024 | 7 |
_a10.1007/978-3-540-33990-8 _2doi |
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050 | 4 | _aR895-920 | |
072 | 7 |
_aMMPH _2bicssc |
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072 | 7 |
_aMMP _2bicssc |
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072 | 7 |
_aMED008000 _2bisacsh |
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082 | 0 | 4 |
_a616.0757 _223 |
245 | 1 | 0 |
_aTechnetium-99m Pharmaceuticals _h[electronic resource] : _bPreparation and Quality Control in Nuclear Medicine / _cedited by Ilse Zolle. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2007. |
|
300 |
_aXX, 345 p. 66 illus., 1 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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505 | 0 | _aI -- Drug Safety -- Technetium in Medicine -- Stannous Chloride in the Preparation of 99mTc Pharmaceuticals -- Quality Assurance of Radiopharmaceuticals -- Performance and Quality Control of the 99Mo/99mTc Generator -- Preparation of Technetium 99mTc Pharmaceuticals -- Lyophilization Technique for Preparing Radiopharmaceutical Kits -- Cellular Labeling with 99mTc Chelates: Relevance of In Vitro and In Vivo Viability Testing -- Quality Control Methods of 99mTc Pharmaceuticals -- Other Technetium Isotopes: 94mTc as a Potential Substitute in Positron Emission Tomography Investigations -- The Rules Governing Medicinal Products for Human Use in the European Union -- II -- Monographs of 99mTc Pharmaceuticals. | |
520 | _aThis textbook gives an account of the accomplishments related to the development of 99mTc-radiopharmaceuticals and their application in diagnostic nuclear medicine. Since radioactive drug development is a multi-disciplinary task, experts working in nuclear medicine and research institutions have contributed valuable information concerning the preparation with sterile kits, methods of quality control, and the use of 99mTc-radiopharmaceuticals in patients. In addition, the legal aspects governing production and clinical application are also considered. Section 1 contains basic principles and methods used for analysis. Special emphasis is given to the analytical methods verifying pharmaceutical quality. Section 2 contains monographs of 99mTc-radiopharmaceuticals used in nuclear medicine. Each monograph includes information on the chemistry, formulation, commercial products and trade names, factors affection in-vivo performance, clinical information on pharmacokinetics, as well as details concerning the clinical application and the radiation dose to patients. This book can serve for daily practice in nuclear medicine, serving as a reference source as well as a teaching tool. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aRadiology. | |
650 | 0 | _aNuclear medicine. | |
650 | 1 | 4 | _aMedicine & Public Health. |
650 | 2 | 4 | _aImaging / Radiology. |
650 | 2 | 4 | _aNuclear Medicine. |
700 | 1 |
_aZolle, Ilse. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540339892 |
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-3-540-33990-8 |
912 | _aZDB-2-SME | ||
950 | _aMedicine (Springer-11650) | ||
999 |
_c503416 _d503416 |