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001			978-1-59745-001-0
003			DE-He213
005			20161121230736.0
007			cr nn 008mamaa
008			100301s2007 xxu| s |||| 0|eng d
020			_a9781597450010 _9978-1-59745-001-0
024	7		_a10.1007/978-1-59745-001-0 _2doi
050		4	_aRC681-688.2
072		7	_aMJD _2bicssc
072		7	_aMED010000 _2bisacsh
082	0	4	_a616.12 _223
245	1	0	_aEssentials of Restenosis _h[electronic resource] : _bFor the Interventional Cardiologist / _cedited by Henricus J. Duckers, Elizabeth G. Nabel, Patrick W. Serruys.
264		1	_aTotowa, NJ : _bHumana Press, _c2007.
300			_aXIV, 458 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aContemporary Cardiology
505	0		_aPathophysiology and Diagnosis -- Unraveling the Complex Process of Restenosis From Bench to Bedside -- Epidemiology and Pathogenesis of Restenosis -- Clinical Presentation of Restenosis -- Pathological Anatomy of Restenosis -- The Influence of Shear Stress on Restenosis -- The Immune System in the Pathogenesis of Vascular Proliferative Disease -- Animal Restenosis Models -- Genetic Basis of Restenosis -- The Genomics of Restenosis -- Gene-Expression Profiling and Restenosis -- Proteomics and Restenosis -- Contribution of Circulating Progenitor Cells to Vascular Repair and Lesion Formation -- Cell Cycle Regulators and Vascular Proliferative Diseases -- Arterial Remodeling -- The Role of eNOS in Vascular Diseases -- Diagnosis of Restenosis -- The Use of Pressure Gradient in the Diagnosis of Restenosis -- The Use of Radio Isotopes in the Diagnosis of Vascular Proliferative Disease -- Magnetic Resonance Imaging for Restenosis -- Coronary Imaging With Multislice Spiral Computed Tomography -- Therapy of Restenosis -- Pharmacotherapy of Restenosis -- Brachytherapy -- Preclinical Data of Eluting Stents -- Clinical Data of Eluting Stents -- Biodegradable Stents -- Biotechnology in the Treatment of Restenosis -- Vascular Gene Therapy -- Antisense and ODN Transcription Factors in the Treatment of Vascular Proliferative Disease -- Cell Cycle Approaches to the Treatment of In-Stent Restenosis -- Local Gene and Cell Delivery Devices.
520			_aEssentials of Restenosis provides the practicing cardiologists and biologists an elaborate review of the current advances in the field. Authors explore the process of restenosis from bench to bedside, encompassing in equal detail the newest scientific findings of the biological mechanisms as well as the progression in development of diagnostics and treatments. The volume also provides the reader with a basic understanding of the biological process and the latest diagnostics and treatments of the disease, with an up-to-date detailed discussion of the most important recent findings. Leading interventional cardiologists, including Patrick Serruys, Eric Topol, David Holmes, Thomas Luscher and others provide the gold-standard reference on the treatment of restenosis (coronary artery blockage) for interventional cardiologists. Dr. Serruys, who pioneered the use of drug-eluting stents, and other pioneers in the field cover everything from non-invasive imaging, to eluting stents, to brachytherapy through to the latest molecular biology-based treatments including antisense, stem cells and gene therapy, making this an essential reference for all interventional cardiologists. Thorough chapters discuss the current understanding on the pathophysiology, molecular and genetic base, and methods of diagnosis of restenosis, and present the current state-of-the-art management, including pharmacotherapy and interventional percutaneous approaches using brachytherapy, gene therapy and drug eluting stent technology. All this makes Essentials of Restenosis an excellent handbook for introducing new intervention cardiologists, vascular biologists, and medical students into the subject. This text provides the reader with a complete overview of the basic and applied knowledge of restenosis, leading to better insight and decision-making in clinical practice.
650		0	_aMedicine.
650		0	_aInterventional radiology.
650		0	_aInternal medicine.
650		0	_aCardiology.
650		0	_aVascular surgery.
650	1	4	_aMedicine & Public Health.
650	2	4	_aCardiology.
650	2	4	_aVascular Surgery.
650	2	4	_aInternal Medicine.
650	2	4	_aInterventional Radiology.
700	1		_aDuckers, Henricus J. _eeditor.
700	1		_aNabel, Elizabeth G. _eeditor.
700	1		_aSerruys, Patrick W. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588294913
830		0	_aContemporary Cardiology
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-59745-001-0
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c503289 _d503289