000 | 03234nam a22004815i 4500 | ||
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001 | 978-0-387-74672-2 | ||
003 | DE-He213 | ||
005 | 20161121230735.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2007 xxu| s |||| 0|eng d | ||
020 |
_a9780387746722 _9978-0-387-74672-2 |
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024 | 7 |
_a10.1007/978-0-387-74672-2 _2doi |
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050 | 4 | _aRC648-665.2 | |
072 | 7 |
_aMJG _2bicssc |
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072 | 7 |
_aMED027000 _2bisacsh |
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082 | 0 | 4 |
_a616.4 _223 |
245 | 1 | 0 |
_aRelaxin and Related Peptides _h[electronic resource] / _cedited by Alexander I. Agoulnik. |
264 | 1 |
_aNew York, NY : _bSpringer New York, _c2007. |
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300 |
_aXXII, 142 p. 44 illus., 4 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
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490 | 1 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v612 |
|
505 | 0 | _aThe Evolution of the Relaxin Peptide Family and Their Receptors -- Relaxin, the Relaxin-Like Factor and Their Receptors -- Diverse Signalling Mechanisms Used by Relaxin in Natural Cells and Tissues: The Evolution of a “Neohormone” -- Relaxin Physiology in the Female Reproductive Tract during Pregnancy -- Relaxin and Related Peptides in Male Reproduction -- The Vascular Actions of Relaxin -- The Effects of Relaxin on Extracellular Matrix Remodeling in Health and Fibrotic Disease -- Relaxin-Like Ligand-Receptor Systems Are Autocrine/Paracrine Effectors in Tumor Cells and Modulate Cancer Progression and Tissue Invasiveness -- Relaxin-Family Peptide and Receptor Systems in Brain: Insights from Recent Anatomical and Functional Studies. | |
520 | _aRelaxin and Related Peptides discusses the established paradigms, the contradictions, and the most recent findings and future directions in the field of relaxin research. The array of diverse topics are highlighted, ranging from evolution of relaxin family peptides and receptors to their cell signaling, from the role of relaxin in reproduction to the newly discovered functions in cancer progression and in the nervous system. The four major ongoing areas of research described in this book will likely attract investigators for years to come, since many basic scientific questions remain unanswered at this time. The availability of structural databases, new experimental techniques, and high quality hormone preparations, antibodies and other reagents enable rigorous investigation. Relaxin and Related Peptides offers a fresh perspective along with different points of view, opinions and disagreements. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aEndocrinology. | |
650 | 0 | _aCell biology. | |
650 | 1 | 4 | _aMedicine & Public Health. |
650 | 2 | 4 | _aEndocrinology. |
650 | 2 | 4 | _aCell Biology. |
650 | 2 | 4 | _aCancer Research. |
700 | 1 |
_aAgoulnik, Alexander I. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9780387746708 |
830 | 0 |
_aAdvances in Experimental Medicine and Biology, _x0065-2598 ; _v612 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/978-0-387-74672-2 |
912 | _aZDB-2-SME | ||
950 | _aMedicine (Springer-11650) | ||
999 |
_c503272 _d503272 |