000 03234nam a22004815i 4500
001 978-0-387-74672-2
003 DE-He213
005 20161121230735.0
007 cr nn 008mamaa
008 100301s2007 xxu| s |||| 0|eng d
020 _a9780387746722
_9978-0-387-74672-2
024 7 _a10.1007/978-0-387-74672-2
_2doi
050 4 _aRC648-665.2
072 7 _aMJG
_2bicssc
072 7 _aMED027000
_2bisacsh
082 0 4 _a616.4
_223
245 1 0 _aRelaxin and Related Peptides
_h[electronic resource] /
_cedited by Alexander I. Agoulnik.
264 1 _aNew York, NY :
_bSpringer New York,
_c2007.
300 _aXXII, 142 p. 44 illus., 4 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v612
505 0 _aThe Evolution of the Relaxin Peptide Family and Their Receptors -- Relaxin, the Relaxin-Like Factor and Their Receptors -- Diverse Signalling Mechanisms Used by Relaxin in Natural Cells and Tissues: The Evolution of a “Neohormone” -- Relaxin Physiology in the Female Reproductive Tract during Pregnancy -- Relaxin and Related Peptides in Male Reproduction -- The Vascular Actions of Relaxin -- The Effects of Relaxin on Extracellular Matrix Remodeling in Health and Fibrotic Disease -- Relaxin-Like Ligand-Receptor Systems Are Autocrine/Paracrine Effectors in Tumor Cells and Modulate Cancer Progression and Tissue Invasiveness -- Relaxin-Family Peptide and Receptor Systems in Brain: Insights from Recent Anatomical and Functional Studies.
520 _aRelaxin and Related Peptides discusses the established paradigms, the contradictions, and the most recent findings and future directions in the field of relaxin research. The array of diverse topics are highlighted, ranging from evolution of relaxin family peptides and receptors to their cell signaling, from the role of relaxin in reproduction to the newly discovered functions in cancer progression and in the nervous system. The four major ongoing areas of research described in this book will likely attract investigators for years to come, since many basic scientific questions remain unanswered at this time. The availability of structural databases, new experimental techniques, and high quality hormone preparations, antibodies and other reagents enable rigorous investigation. Relaxin and Related Peptides offers a fresh perspective along with different points of view, opinions and disagreements.
650 0 _aMedicine.
650 0 _aCancer research.
650 0 _aEndocrinology.
650 0 _aCell biology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aEndocrinology.
650 2 4 _aCell Biology.
650 2 4 _aCancer Research.
700 1 _aAgoulnik, Alexander I.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387746708
830 0 _aAdvances in Experimental Medicine and Biology,
_x0065-2598 ;
_v612
856 4 0 _uhttp://dx.doi.org/10.1007/978-0-387-74672-2
912 _aZDB-2-SME
950 _aMedicine (Springer-11650)
999 _c503272
_d503272