000 03081nam a22004335i 4500
001 978-3-540-30773-0
003 DE-He213
005 20161121230706.0
007 cr nn 008mamaa
008 100301s2006 gw | s |||| 0|eng d
020 _a9783540307730
_9978-3-540-30773-0
024 7 _a10.1007/3-540-30773-7
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aReoviruses: Entry, Assembly and Morphogenesis
_h[electronic resource] /
_cedited by Polly Roy.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2006.
300 _aXIX, 268 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v309
505 0 _aAttachment and Cell Entry of Mammalian Orthoreovirus -- Early Steps in Rotavirus Cell Entry -- Early Steps in Avian Reovirus Morphogenesis -- Bluetongue Virus Assembly and Morphogenesis -- Reovirus Structure and Morphogenesis -- Rotavirus Genome Replication and Morphogenesis: Role of the Viroplasm -- Rotavirus Proteins: Structure and Assembly -- Structural Studies on Orbivirus Proteins and Particles -- Rotavirus Assembly: An Alternative Model That Utilizes an Atypical Trafficking Pathway.
520 _aReoviridae family members are large, complex viruses that infect human, animals, plants and insects. They are unique in that they lack lipid envelopes and package their genomes of discrete double-stranded segments of RNA within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses to be obtained. The capsids of these viruses undergo cell entry, uncoating, the enzymatic functions necessary for transcription of the genome, and are later involved in egress from host cells. Recent years have seen an increase in our knowledge of the structure of these viruses coupled with substantial progress in unravelling the molecular details of these processes. Intriguingly, despite their diversity in hosts, structures and modes of transmission, striking parallels have emerged in the molecular interactions necessary for the essential processes of virus entry, assembly and release. This book reviews our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of viral proteins and capsids from three different genera of the family.
650 0 _aMedicine.
650 0 _aVirology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
700 1 _aRoy, Polly.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540307723
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v309
856 4 0 _uhttp://dx.doi.org/10.1007/3-540-30773-7
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502546
_d502546