000 | 03009nam a22004455i 4500 | ||
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001 | 978-3-540-29933-2 | ||
003 | DE-He213 | ||
005 | 20161121230706.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2005 gw | s |||| 0|eng d | ||
020 |
_a9783540299332 _9978-3-540-29933-2 |
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024 | 7 |
_a10.1007/3-540-29933-5 _2doi |
|
050 | 4 | _aRC261-271 | |
072 | 7 |
_aMJCL _2bicssc |
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072 | 7 |
_aMED062000 _2bisacsh |
|
082 | 0 | 4 |
_a614.5999 _223 |
245 | 1 | 0 |
_aChronic Lymphocytic Leukemia _h[electronic resource]. |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2005. |
|
300 |
_aX, 190 p. 40 illus., 5 illus. in color. _bonline resource. |
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336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
||
338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v294 |
|
505 | 0 | _aB Cell Development and Its Deregulation to Transformed States at the Pre-B Cell Receptor-Expressing Pre-BII Cell Stage -- Gene Expression Patterns in Human and Mouse B Cell Development -- New Insights into the Phenotype and Cell Derivation of B Cell Chronic Lymphocytic Leukemia -- Chronic Lymphocytic Leukemia: Molecular Genetics and Animal Models -- What Do Somatic Hypermutation and Class Switch Recombination Teach Us About Chronic Lymphocytic Leukaemia Pathogenesis? -- Chronic Lymphocytic Leukaemia: A Review of the Immuno-architecture -- Clinical and Laboratory Parameters That Define Clinically Relevant B-CLL Subgroups -- Differential Effects on CLL Cell Survival Exerted by Different Microenvironmental Elements -- Genotypic Prognostic Markers -- Chronic Lymphocytic Leukaemia: Clinical Translations of Biological Features. | |
520 | _aChronic lymphocytic leukaemia (CLL) is the most common leukaemia in the Western world. It is also the prototype of B-cell chronic lymphoid malignancies and of their ramifications within the fields of hematology, immunology and oncology. For a long time the Cinderella of lymphoid malignancies CLL has now become the focus of major interest and an increasing number of investigators from different areas, including genetics, molecular biology, basic and applied immunology are becoming actively engaged in the investigation of CLL. Clinicians are considering CLL as a very interesting target of many projects which aim at translating the new and exciting developments of basic science into effective new approaches to the patient. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aCancer research. | |
650 | 0 | _aHematology. | |
650 | 1 | 4 | _aBiomedicine. |
650 | 2 | 4 | _aCancer Research. |
650 | 2 | 4 | _aHematology. |
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540252795 |
830 | 0 |
_aCurrent Topics in Microbiology and Immunology, _x0070-217X ; _v294 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/3-540-29933-5 |
912 | _aZDB-2-SBL | ||
950 | _aBiomedical and Life Sciences (Springer-11642) | ||
999 |
_c502536 _d502536 |