000 02802nam a22004455i 4500
001 978-3-540-27511-4
003 DE-He213
005 20161121230704.0
007 cr nn 008mamaa
008 100301s2005 gw | s |||| 0|eng d
020 _a9783540275114
_9978-3-540-27511-4
024 7 _a10.1007/3-540-27511-8
_2doi
050 4 _aQR355-502
072 7 _aMMFM
_2bicssc
072 7 _aMED052000
_2bisacsh
082 0 4 _a616.9101
_223
245 1 0 _aBacterial Virulence Factors and Rho GTPases
_h[electronic resource] /
_cedited by Patrice Boquet, Emmanuel Lemichez.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2005.
300 _aX, 198 p. 28 illus., 20 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v291
505 0 _aBacterial Virulence Strategies That Utilize Rho GTPases -- Extracellular Bacterial Pathogens and Small GTPases of the Rho Family: An Unexpected Combination -- Triggered Phagocytosis by Salmonella: Bacterial Molecular Mimicry of RhoGTPase Activation/Deactivation -- Regulation of Phagocytosis by Rho GTPases -- The Immunological Synapse and Rho GTPases -- Rho GTPases and the Control of the Oxidative Burst in Polymorphonuclear Leukocytes -- Clostridial Rho-Inhibiting Protein Toxins -- The Type III Cytotoxins of Yersinia and Pseudomonas aeruginosa That Modulate the Actin Cytoskeleton -- Modulation of Rho GTPases and the Actin Cytoskeleton by YopT of Yersinia -- Bacterial Toxins Activating Rho GTPases.
520 _aPathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The first role of these virulence factors is to loosen the host defenses against microorganisms represented by innate and adaptive immunities. Small GTPases of the Rho subfamily have been shown top play important functions in theses systems. The authors of this volume present the synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfill their virulence.
650 0 _aMedicine.
650 0 _aVirology.
650 1 4 _aBiomedicine.
650 2 4 _aVirology.
700 1 _aBoquet, Patrice.
_eeditor.
700 1 _aLemichez, Emmanuel.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540238652
830 0 _aCurrent Topics in Microbiology and Immunology,
_x0070-217X ;
_v291
856 4 0 _uhttp://dx.doi.org/10.1007/3-540-27511-8
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502486
_d502486