000 02595nam a22004575i 4500
001 978-3-540-26954-0
003 DE-He213
005 20161121230703.0
007 cr nn 008mamaa
008 100301s2005 gw | s |||| 0|eng d
020 _a9783540269540
_9978-3-540-26954-0
024 7 _a10.1007/b138362
_2doi
050 4 _aRC261-271
072 7 _aMJCL
_2bicssc
072 7 _aMED062000
_2bisacsh
082 0 4 _a614.5999
_223
100 1 _aCooper, David N.
_eauthor.
245 1 4 _aThe Molecular Genetics of Lung Cancer
_h[electronic resource] /
_cby David N. Cooper.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2005.
300 _aXVI, 392 p. 34 illus., 13 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aAn Introduction to the Molecular Basis of Cancer -- Lung Cancer: Setting the Scene -- Genes Involved in Sporadic Forms of Lung Cancer -- Somatic Mutation in Lung Cancer -- Genetic Approaches to Studying the Association Between Smoking and Lung Cancer -- Evidence for Genetic Susceptibility to Lung Cancer Derived from Polymorphism-disease Association Studies -- Gene Expression Studies in Lung Cancer -- Lung Cancer Pathogenesis and Future Prospects for Treatment and Prevention.
520 _aLung cancer is the leading cause of cancer mortality in Western countries. It also provides an archetypal example of how inherited predisposing genetic variants may interact with an environmental influence (smoking) to modulate individual cancer risk. The Molecular Genetics of Lung Cancer describes how the new techniques, methods and approaches of molecular genetics are being used to unravel the complexities of the mechanisms underlying lung tumorigenesis by analysis at the DNA, RNA and protein levels with potentially important implications for tumour classification, diagnosis, prognosis and treatment as well as providing new insights into how lung tumours arise and how they progress to malignancy.
650 0 _aMedicine.
650 0 _aCancer research.
650 0 _aHuman genetics.
650 0 _aOncology.
650 1 4 _aBiomedicine.
650 2 4 _aCancer Research.
650 2 4 _aOncology.
650 2 4 _aHuman Genetics.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540229858
856 4 0 _uhttp://dx.doi.org/10.1007/b138362
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502470
_d502470