000			03433nam a22004815i 4500
001			978-1-59259-833-5
003			DE-He213
005			20161121230701.0
007			cr nn 008mamaa
008			100301s2005 xxu| s |||| 0|eng d
020			_a9781592598335 _9978-1-59259-833-5
024	7		_a10.1385/1592598331 _2doi
050		4	_aRB155-155.8
050		4	_aQH431
072		7	_aMFN _2bicssc
072		7	_aMED107000 _2bisacsh
082	0	4	_a611.01816 _223
082	0	4	_a599.935 _223
245	1	4	_aThe Principles of Clinical Cytogenetics _h[electronic resource] / _cedited by Steven L. Gersen, Martha B. Keagle.
250			_aSecond Edition.
264		1	_aTotowa, NJ : _bHumana Press : _bImprint: Humana Press, _c2005.
300			_aXIII, 596 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aBasic Concepts and Background -- History of Clinical Cytogenetics -- DNA, Chromosomes, and Cell Division -- Human Chromosome Nomenclature -- Examining and Analyzing Chromosomes -- Basic Laboratory Procedures -- The Fundamentals of Microscopy -- Quality Control and Quality Assurance -- Instrumentation in the Cytogenetics Laboratory -- Clinical Cytogenetics -- Autosomal Aneuploidy -- Structural Chromosome Rearrangements -- Sex Chromosomes and Sex Chromosome Abnormalities -- Cytogenetics of Infertility -- Prenatal Cytogenetics -- Cytogenetics of Spontaneous Abortion -- Chromosome Instability -- Cancer Cytogenetics -- Cytogenetics of Hematologic Neoplasms -- Cytogenetics of Solid Tumors -- Fluorescence In Situ Hybridization -- Fluorescence In Situ Hybridization -- Beyond Chromosomes -- Fragile X -- Genomic Imprinting and Uniparental Disomy -- Genetic Counseling.
520			_aIn this thoroughly revised and expanded edition of a highly praised classic, The Principles of Clinical Cytogenetics, a panel of hands-on experts update their survey of the basic concepts and interpretations involved in chromosome analysis to include the many advances that have occurred in the field. Among the highlights are a full section devoted to advances in fluorescence in situ hybridization (FISH) technology, increased coverage of cancer cytogenetics-both hematopoietic neoplasms and tumor cytogenetics-and new chapters on chromosome instability and the cytogenetics of infertility. The book also reflects major advances in instrumentation and the transition from FAB to World Health Organization nomenclature for hematopoietic disorders. State-of-the-art and readily accessible, The Principles of Clinical Cytogenetics, 2nd Edition offers physicians who depend on the cytogenetics laboratory for the diagnosis of their patients, students in cytogenetics programs, and cytogeneticists the clear understanding they need to carry out and interpret their test results rapidly.
650		0	_aMedicine.
650		0	_aHuman genetics.
650		0	_aPathology.
650	1	4	_aBiomedicine.
650	2	4	_aHuman Genetics.
650	2	4	_aPathology.
700	1		_aGersen, Steven L. _eeditor.
700	1		_aKeagle, Martha B. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588293008
856	4	0	_uhttp://dx.doi.org/10.1385/1592598331
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c502428 _d502428