000 02576nam a22004815i 4500
001 978-0-387-34573-4
003 DE-He213
005 20161121230654.0
007 cr nn 008mamaa
008 100301s2006 xxu| s |||| 0|eng d
020 _a9780387345734
_9978-0-387-34573-4
024 7 _a10.1007/0-387-34573-6
_2doi
050 4 _aQR180-189.5
072 7 _aMJCM
_2bicssc
072 7 _aMED044000
_2bisacsh
082 0 4 _a616.079
_223
100 1 _aWajant, Harald.
_eauthor.
245 1 0 _aFas Signaling
_h[electronic resource] /
_cby Harald Wajant.
264 1 _aBoston, MA :
_bSpringer US,
_c2006.
300 _aVIII, 160 p. 32 illus., 4 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMedical Intelligence Unit
505 0 _aFasL and Fas -- FasL-Independent Activation of Fas -- Role of Ceramide in CD95 Signaling -- Regulation of Fas Signaling by FLIP Proteins -- Fas-Induced Necrosis -- Fas—More Than an Apoptosis Inducer -- Retrograde Fas Ligand Signaling -- FasL and Fas in Liver Homeostasis and Hepatic Injuries -- Fas-Activation, Development and Homeostasis of T Cells -- The FasL-Fas System in Disease and Therapy -- Tools for Activation and Neutralization of Fas Signaling.
520 _aFas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aMolecular biology.
650 0 _aOncology.
650 1 4 _aBiomedicine.
650 2 4 _aImmunology.
650 2 4 _aMolecular Medicine.
650 2 4 _aOncology.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387321721
830 0 _aMedical Intelligence Unit
856 4 0 _uhttp://dx.doi.org/10.1007/0-387-34573-6
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502230
_d502230