000			03709nam a22004455i 4500
001			978-0-387-32823-2
003			DE-He213
005			20161121230652.0
007			cr nn 008mamaa
008			100301s2006 xxu| s |||| 0|eng d
020			_a9780387328232 _9978-0-387-32823-2
024	7		_a10.1007/0-387-32823-2 _2doi
050		4	_aRC321-580
072		7	_aPSAN _2bicssc
072		7	_aMED057000 _2bisacsh
082	0	4	_a612.8 _223
245	1	0	_aRestorative Therapies in Parkinson's Disease _h[electronic resource] / _cedited by Patrik Brundin, C. Warren Olanow.
264		1	_aBoston, MA : _bSpringer US, _c2006.
300			_aXVII, 365 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aRestorative Therapies in a Historical Perspective -- Ethical Issues in the Approaches of Restorative Therapies for Parkinson's Disease -- Evolution of Parkinson's Disease and Treatment Requirements -- What New Treatments are Needed and the Role of Striatal Grafting -- Clinical Trial Design Issues -- Lessons Learnt from Early Clinical Neural Grafting in Parkinson's Disease -- Fetal Nigral Transplantation as a Therapy for Parkinson’s Disease -- Imaging of the Parkinsonian Brain in Relation to Restorative Therapy -- Important Aspects of Surgical Methodology for Transplantation in Parkinson’s Disease -- Histopathological and Clinical Criteria for Analyzing Transplanted Human Dopamine Cells in Parkinson's Disease -- Dyskinesias and Neural Grafting in Parkinson's Disease -- Porcine Neural Xenotransplantation: Current Status -- Adult-Derived Stem Cells for Transplantation in Parkinson's Disease -- Embryonic Stem Cells for Grafting in Parkinson's Disease -- Delivery of GDNF For Parkinson's Disease: Transition of a Neuroprotective Treatment Strategy from Basic Sciences to Clinical Application -- Genetically Modified Cells as a Source for Grafting in Parkinson'se Disease -- In Vivo Gene Therapy as a Potential Treatment for Parkinson's Disease.
520			_aParkinson’s disease is a common and devastating progressive disorder that primarily affects motor function. In this exciting and timely book, novel approaches to repairing the parkinsonian brain are described by some of the world’s leading scientists and clinicians in the field. Dealing with cutting-edge research, it covers several important topics including medical ethics, clinical trial design, stem cell biology, intracerebral transplantation, brain imaging, neurotrophic factors and neural regeneration. The comprehensive chapters are geared to an audience of neuroscientists, neurologists, neurosurgeons and anyone interested in how findings in the research laboratory can effectively be transferred to the clinic. Restorative therapies in Parkinson’s disease have pioneered translational research in the area of brain repair for close to three decades. This book clearly shows that research in Parkinson’s disease continues to play a leading role and can provide a model for how functional restoration might be achieved in several brain disorders in the future.
650		0	_aMedicine.
650		0	_aNeurosciences.
650		0	_aNeurology.
650	1	4	_aBiomedicine.
650	2	4	_aNeurosciences.
650	2	4	_aNeurology.
700	1		_aBrundin, Patrik. _eeditor.
700	1		_aOlanow, C. Warren. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387299846
856	4	0	_uhttp://dx.doi.org/10.1007/0-387-32823-2
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c502196 _d502196