000 03820nam a22005295i 4500
001 978-0-387-30678-0
003 DE-He213
005 20161121230651.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387306780
_9978-0-387-30678-0
024 7 _a10.1007/0-387-30678-1
_2doi
050 4 _aQH491
072 7 _aPSC
_2bicssc
072 7 _aSCI072000
_2bisacsh
082 0 4 _a571.8
_223
245 1 0 _aDevelopment of the Inner Ear
_h[electronic resource] /
_cedited by Matthew W. Kelley, Doris K. Wu, Arthur N. Popper, Richard R. Fay.
264 1 _aNew York, NY :
_bSpringer New York,
_c2005.
300 _aXII, 242 p. 34 illus., 4 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aSpringer Handbook of Auditory Research,
_x0947-2657 ;
_v26
505 0 _aDevelopmental Neurobiology of the Ear: Current Status and Future Directions -- The Induction of the Otic Placode -- Morphogenesis of the Inner Ear -- Wiring the Ear to the Brain: The Molecular Basis of Neurosensory Development, Differentiation, and Survival -- Notch Signaling and Cell Fate Determination in the Vertebrate Inner Ear -- The Differentiation of Hair Cells -- Developmental Genes Associated with Human Hearing Loss.
520 _aThis book describes the embryonic development of the vertebrate inner ear in six chapters that span all aspects of inner ear development, from the induction of the otic placode through cellular morphogenesis, to the onset of auditory function. In each chapter, a particular aspect of development of the inner ear is examined in terms of both classic embryologic experiments and more recent advances using molecular biological techniques. The publication of this volume is particularly timely in light of recent significant advances in molecular biological and cellular imaging techniques. These changes have led to an explosion in the pace of developmental inner ear research that is clearly reflected in the chapters presented here. The book will serve as a useful resource for scientists who study inner ear biology, as well as developmental biologists who work in other systems, but have an interest in an overview of the developing ear. This book will also be a valuable resource for clinicians who wish to know more about the development of the ear and about the genetic and molecular factors that regulate its formation. Matthew Kelley and Doris Wu are both Investigators at the National Institute on Deafness and other Communication Disorders at the National Institutes of Health, Bethesda, Maryland. Arthur N. Popper is Professor in the Department of Biology and Co-Director of the Center for Comparative and Evolutionary Biology of Hearing at the University of Maryland, College Park. Richard R. Fay is Director of the Parmly Hearing Institute and Professor of Psychology at Loyola University of Chicago.
650 0 _aLife sciences.
650 0 _aNeurosciences.
650 0 _aDevelopmental biology.
650 0 _aMicrobiology.
650 1 4 _aLife Sciences.
650 2 4 _aDevelopmental Biology.
650 2 4 _aNeurosciences.
650 2 4 _aMicrobiology.
650 2 4 _aLife Sciences, general.
700 1 _aKelley, Matthew W.
_eeditor.
700 1 _aWu, Doris K.
_eeditor.
700 1 _aPopper, Arthur N.
_eeditor.
700 1 _aFay, Richard R.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387250687
830 0 _aSpringer Handbook of Auditory Research,
_x0947-2657 ;
_v26
856 4 0 _uhttp://dx.doi.org/10.1007/0-387-30678-1
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502173
_d502173