000 03102nam a22004575i 4500
001 978-0-387-26476-9
003 DE-He213
005 20161121230649.0
007 cr nn 008mamaa
008 100301s2005 xxu| s |||| 0|eng d
020 _a9780387264769
_9978-0-387-26476-9
024 7 _a10.1007/b137670
_2doi
050 4 _aQH506
072 7 _aMBGR
_2bicssc
072 7 _aPSD
_2bicssc
072 7 _aSCI049000
_2bisacsh
072 7 _aMED067000
_2bisacsh
082 0 4 _a611.01816
_223
100 1 _aRazzaque, Mohammed S.
_eauthor.
245 1 0 _aFibrogenesis: Cellular and Molecular Basis
_h[electronic resource] /
_cby Mohammed S. Razzaque.
264 1 _aBoston, MA :
_bSpringer US,
_c2005.
300 _aXVI, 216 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aMedical Intelligence Unit
505 0 _aTissue Scarring -- Pathological Significance of Renal Expression of Proinflammatory Molecules -- Oxidative Stress, Lipoproteins and Angiotensin II -- Involvement of NF-?B in Renal Inflammation and Sclerosis -- Low-Denisty Lipoprotein and Glomerulosclerosis -- Molecular Developments in the Treatment of Renal Fibrosis -- Myocardial Infarction and Cardiac Fibrogenesis -- Cardiac Fibrosis and Aging -- Matrix Remodeling and Atherosclerosis Effect of Age -- Molecular and Cellular Aspects of Liver Fibrosis -- Recent Therapeutic Developments in Hepatic Fibrosis -- Reversibility of Liver Fibrosis -- Can Manipulation of Apoptotic Cell Death Benefit Tissue Scarring? -- Pulmonary Fibrogenesis -- Silica-Induced Inflammatory Mediators and Pulmonary Fibrosis.
520 _aFibrogenesis: Cellular and Molecular Basis is the first volume to provide a synopsis of the rapid progress that has been documented in fibrogenesis over last couple of years, which significantly enhanced our understanding of the pathomechanisms of fibrotic diseases. Knowledge on molecular and celluar basis of fibrotic diseases has provided opportunities to develop selective and effective gene-based therapeutic options. The chapters in this book have been selected to provide comprehensive information on fibrogenesis, which is not limited to any specific organ. Individual chapters present mechanisms of fibrotic diseases involving lung, liver, kidney, heart, blood vessels, and more. The relevance and significance of inflammatory cytokines, chemokines, transcriptional factors, fibrogenic molecules, signaling cascade, and matrix remodeling in fibrogenesis are explained in depth, providing the reader with current and updated information.
650 0 _aMedicine.
650 0 _aMolecular biology.
650 1 4 _aBiomedicine.
650 2 4 _aMolecular Medicine.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780306478611
830 0 _aMedical Intelligence Unit
856 4 0 _uhttp://dx.doi.org/10.1007/b137670
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502110
_d502110