000 04329nam a22004455i 4500
001 978-0-387-25858-4
003 DE-He213
005 20161121230649.0
007 cr nn 008mamaa
008 100301s2006 xxu| s |||| 0|eng d
020 _a9780387258584
_9978-0-387-25858-4
024 7 _a10.1007/b136263
_2doi
050 4 _aRC321-580
072 7 _aPSAN
_2bicssc
072 7 _aMED057000
_2bisacsh
082 0 4 _a612.8
_223
245 1 0 _aAdvances in Network Electrophysiology
_h[electronic resource] :
_bUsing Multi-Electrode Arrays /
_cedited by Makoto Taketani, Michel Baudry.
264 1 _aBoston, MA :
_bSpringer US,
_c2006.
300 _aXVIII, 478 p. 222 illus., 13 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
505 0 _aDevelopment of MEA for Cells, Acute Slices, and Cultured Tissues -- A History of MEA Development -- On Micro-Electrode Array Revival: Its Development, Sophistication of Recording, and Stimulation -- Multi-Electrode Arrays: Enhancing Traditional Methods and Enabling Network Physiology -- Development of 3-D Multi-Electrode Arrays for Use with Acute Tissue Slices -- Electrophysiological Monitoring of Hippocampal Slice Cultures Using MEA on Porous Membrane -- Mapping Spatio-Temporal Electrophysiological Activity in Hippocampal Slices with Conformal Planar Multi-Electrode Arrays -- Pattern Technologies for Structuring Neuronal Networks on MEAs -- MEA Applications: Dissociated Cell Cultures -- Emerging Histiotypic Properties of Cultured Neuronal Networks -- Closing the Loop: Stimulation Feedback Systems for Embodied MEA Cultures -- Emerging Network Activity in Dissociated Cultures of Neocortex: Novel Electrophysiological Protocols and Mathematical Modeling -- Analysis of Cardiac Myocyte Activity Dynamics with Micro-Electrode Arrays -- MEA Applications: Acute/Cultured Slices -- A Hippocampal-Based Biosensor for Neurotoxins Detection and Classification Using a Novel Short-Term Plasticity Quantification Method -- The Retinasensor: An In Vitro Tool to Study Drug Effects on Retinal Signaling -- Chronic Alcohol Effects on Hippocampal Neuronal Networks -- Applications of Multi-Electrode Array System in Drug Discovery Using Acute and Cultured Hippocampal Slices -- Rhythm Generation in Spinal Cultures: Is It the Neuron or the Network? -- Monitoring the Clock Neuron’s Tick: Circadian Rhythm Analysis Using a Multi-Electrode Array Dish -- Investigation of Network Phenomena in Hippocampal Slices Using Multi-Electrode Recording Arrays -- Exploring Fast Hippocampal Network Oscillations: Combining Multi-Electrode Recordings with Optical Imaging and Patch-Clamp Techniques.
520 _aThis book book is an attempt to review the recent progress in both electronics and computational tools developed to analyze the functional operations of large ensembles of neurons and to provide the readers with a sense of the applications made possible by these technological tools. While considerable progress has been made over the last decades in our understanding of electrophysiological processes at the single channel, single synapse, and single neuron levels, our understanding of electrophysiological processes at the neuronal network level is still in its infancy. This book includes: Technological overviews of multi-electrode arrays (MEAs) and related electronics and software, Applications of MEAs to study ensemble activity of dissociated cell cultures including cardiac myocytes, Applications of the technology for drug discovery using acute and cultured slices. Examples of studies directed at understanding the origins and functions of various rhythmic activities in neuronal ensembles.
650 0 _aMedicine.
650 0 _aNeurosciences.
650 0 _aBiomedical engineering.
650 1 4 _aBiomedicine.
650 2 4 _aNeurosciences.
650 2 4 _aBiomedical Engineering.
700 1 _aTaketani, Makoto.
_eeditor.
700 1 _aBaudry, Michel.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9780387258577
856 4 0 _uhttp://dx.doi.org/10.1007/b136263
912 _aZDB-2-SBL
950 _aBiomedical and Life Sciences (Springer-11642)
999 _c502103
_d502103