000			03352nam a22005295i 4500
001			978-0-387-25741-9
003			DE-He213
005			20161121230648.0
007			cr nn 008mamaa
008			100301s2006 xxu| s |||| 0|eng d
020			_a9780387257419 _9978-0-387-25741-9
024	7		_a10.1007/b135975 _2doi
050		4	_aRC109-216
072		7	_aMJCJ _2bicssc
072		7	_aMED022090 _2bisacsh
082	0	4	_a616.9 _223
245	1	0	_aIn vivo Models of HIV Disease and Control _h[electronic resource] / _cedited by Herman Friedman, Steven Specter, Mauro Bendinelli.
264		1	_aBoston, MA : _bSpringer US, _c2006.
300			_aXVIII, 436 p. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
490	1		_aInfectious Diseases and Pathogenesis, _x1075-1289
505	0		_aHistorical Perspective -- Animal Model Systems of HIV-Diseases -- Chemokines and Their Receptors and the Neuropathogenesis of HIV-1 Infection -- SCID Mice Transplanted With Human Cells as Small Animal Models in AIDS Research -- SIV as a Model for AIDS Pathogenesis Studies -- SIV Infection of Macaques as a Model for AIDS Drug Studies -- FIV as a Model for HIV: An Overview -- FIV as a Model for AIDS Pathogenesis Studies -- Drugs of Abuse, AIDS, and the FIV Model -- FIV as a Model for AIDS Vaccine Studies -- FIV as a Model for HIV Treatment -- Equine Infectious Anemia Virus as a Model for Lentiviral Pathogenesis -- Studies of the Structure of Caprine Arthritis-Encephalitis Virus Surface Envelope Glycoprotein -- Ethical Issues in the Use of Animal Models of Infection and Some Practical Refinements -- Future Perspectives.
520			_aAn AIDS vaccine is still elusive and HIV treatment continues to develop multidrug resistance at alarming rates. Because of the similarities between HIV and immune deficiency infections in a variety of animals, it is only natural that scientists use these animals as models to study pathogenesis, treatment, vaccine development and many other aspects of HIV. Part of the series Infectious Agents and Pathogenesis, this volume reviews the immune deficiency virus in a variety of hosts. Pathogenesis, vaccine and drug development, epidemiology, and the natural history of the monkey, mouse, cat, cow, horse, and other animal viruses are detailed and compared to HIV. Also included are chapters on the history and future of animal models, as well as a chapter on ethical and safety considerations in using animal models for AIDS studies.
650		0	_aMedicine.
650		0	_aImmunology.
650		0	_aAllergy.
650		0	_aInfectious diseases.
650		0	_aMicrobiology.
650	1	4	_aMedicine & Public Health.
650	2	4	_aInfectious Diseases.
650	2	4	_aAllergology.
650	2	4	_aMicrobiology.
650	2	4	_aImmunology.
700	1		_aFriedman, Herman. _eeditor.
700	1		_aSpecter, Steven. _eeditor.
700	1		_aBendinelli, Mauro. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9780387257402
830		0	_aInfectious Diseases and Pathogenesis, _x1075-1289
856	4	0	_uhttp://dx.doi.org/10.1007/b135975
912			_aZDB-2-SBL
950			_aBiomedical and Life Sciences (Springer-11642)
999			_c502101 _d502101