000 03209nam a22005295i 4500
001 978-3-540-37673-6
003 DE-He213
005 20161121230644.0
007 cr nn 008mamaa
008 100301s2006 gw | s |||| 0|eng d
020 _a9783540376736
_9978-3-540-37673-6
024 7 _a10.1007/3-540-37673-9
_2doi
050 4 _aRL1-803
072 7 _aMJK
_2bicssc
072 7 _aMED017000
_2bisacsh
082 0 4 _a616.5
_223
245 1 0 _aCytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases
_h[electronic resource] /
_cedited by R. Numerof, C. A. Dinarello, K. Asadullah.
264 1 _aBerlin, Heidelberg :
_bSpringer Berlin Heidelberg,
_c2006.
300 _aXVII, 209 p.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _atext file
_bPDF
_2rda
490 1 _aErnst Schering Research Foundation Workshop,
_x0947-6075 ;
_v56
505 0 _aInhibition of IFN-? as a Method of Treatment of Various Autoimmune Diseases, Including Skin Diseases -- Cytokine Targeting in Psoriasis and Psoriatic Arthritis: Beyond TNF? -- Inhibitors of Histone Deacetylases as Anti-inflammatory Drugs -- Dendritic Cell Interactions and Cytokine Production -- Lysosomal Cysteine Proteases and Antigen Presentation -- DCs and Cytokines Cooperate for the Induction of Tregs -- Induction of Immunity and Inflammation by Interleukin-12 Family Members -- The Role of TNF? and IL-17 in the Development of Excess IL-1 Signaling-Induced Inflammatory Diseases in IL-1 Receptor Antagonist-Deficient Mice -- TGF?-Mediated Immunoregulation -- TNF Blockade: An Inflammatory Issue -- IL-1 Family Members in Inflammatory Skin Disease -- Regulatory T Cells in Psoriasis.
520 _aCytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytokine signaling pathways are in development. This book summarizes the findings of the 56th International Workshop of the Ernst Schering Research Foundation that focused on "Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases".
650 0 _aMedicine.
650 0 _aImmunology.
650 0 _aAllergy.
650 0 _aDermatology.
650 0 _aCell biology.
650 1 4 _aMedicine & Public Health.
650 2 4 _aDermatology.
650 2 4 _aAllergology.
650 2 4 _aImmunology.
650 2 4 _aCell Biology.
700 1 _aNumerof, R.
_eeditor.
700 1 _aDinarello, C. A.
_eeditor.
700 1 _aAsadullah, K.
_eeditor.
710 2 _aSpringerLink (Online service)
773 0 _tSpringer eBooks
776 0 8 _iPrinted edition:
_z9783540254270
830 0 _aErnst Schering Research Foundation Workshop,
_x0947-6075 ;
_v56
856 4 0 _uhttp://dx.doi.org/10.1007/3-540-37673-9
912 _aZDB-2-SME
950 _aMedicine (Springer-11650)
999 _c502003
_d502003