000 | 04598nam a22006015i 4500 | ||
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001 | 978-3-540-35662-2 | ||
003 | DE-He213 | ||
005 | 20161121230644.0 | ||
007 | cr nn 008mamaa | ||
008 | 100301s2006 gw | s |||| 0|eng d | ||
020 |
_a9783540356622 _9978-3-540-35662-2 |
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024 | 7 |
_a10.1007/3-540-35662-2 _2doi |
|
050 | 4 | _aR895-920 | |
072 | 7 |
_aMMPH _2bicssc |
|
072 | 7 |
_aMMP _2bicssc |
|
072 | 7 |
_aMED008000 _2bisacsh |
|
082 | 0 | 4 |
_a616.0757 _223 |
245 | 1 | 0 |
_aMultimodal Concepts for Integration of Cytotoxic Drugs _h[electronic resource] / _cedited by J. Martin Brown, Minesh P. Mehta, Carsten Nieder. |
246 | 3 | _aWith contributions by numerous experts | |
264 | 1 |
_aBerlin, Heidelberg : _bSpringer Berlin Heidelberg, _c2006. |
|
300 |
_aX, 352 p. 14 illus., 12 illus. in color. _bonline resource. |
||
336 |
_atext _btxt _2rdacontent |
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337 |
_acomputer _bc _2rdamedia |
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338 |
_aonline resource _bcr _2rdacarrier |
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347 |
_atext file _bPDF _2rda |
||
490 | 1 |
_aMedical Radiology, Radiation Oncology, _x0942-5373 |
|
505 | 0 | _aPreclinical Part -- Biological Basis of Combined Radio- and Chemotherapy -- Combinations of Antimetabolites and Ionizing Radiation -- Combinations of Taxanes and Ionizing Radiation -- Combinations of Topoisomerase Inhibitors and Ionizing Radiation -- Combinations of Hypoxia-Targeting Compounds and Radiation-Activated Prodrugs with Ionizing Radiation -- Combinations of Platinum Compounds and Ionizing Radiation -- Combinations of Cytotoxic Drugs, Ionizing Radiation, and Angiogenesis Inhibitors -- Combinations of Cytotoxic Drugs, Ionizing Radiation and EGFR Inhibitors -- Combinations of Cytotoxic Drugs, Ionizing Radiation, and Mammalian Target of Rapamycin (mTOR) Inhibitors -- Combinations of Ionizing Radiation and Other Sensitizing Agents -- Radiotherapy and Tumor-Targeted Drug Delivery -- Clinical Part -- Applications in Malignant Brain Tumors -- Applications in Head and Neck Cancer -- Applications in Esophageal and Gastric Cancer -- Novel Chemoradiation in Localized Pancreatic Cancer: Clinical Studies -- Applications in Lung Cancer -- Integration of Radiation Therapy and Systemic Therapy for Breast Cancer -- Applications in Rectal and Anal Cancer -- Concomitant Radiation and Chemotherapy in Muscle-Invasive Bladder Cancer -- Applications to Gynecological Cancers -- Early and Late Treatment-Induced Toxicity -- Feasibility of Combined Chemo- and Radiation Treatment in Elderly/Comorbid Patients. | |
520 | _aOver recent decades, combined modality treatment has drastically improved the cure rates for various malignant tumors. Further progress is expected through the design of sound combinations involving recently developed drugs. The first part of this book summarizes the rationale and the preclinical data for combined treatment with ionizing radiation and pharmaceutical agents. Individual chapters focus on different forms of combined treatment, with due consideration being given to a range of drugs and to emerging combinations with small molecules and antibodies, derived from recent advances in molecular oncology. The second part of the book comprises a series of disease-specific chapters in which the clinical results of combined modality treatment are presented. In addition, the topics of acute and late toxicity, supportive treatment and tolerance in elderly patients are reviewed. All of the chapters have been written by basic scientists and clinicians who are acknowledged experts in the field. The text is specifically designed to be accessible to professionals from the various disciplines involved in multidisciplinary cancer care and to residents in radiation oncology training programs. | ||
650 | 0 | _aMedicine. | |
650 | 0 | _aRadiology. | |
650 | 0 | _aRadiotherapy. | |
650 | 0 |
_aRespiratory organs _xDiseases. |
|
650 | 0 | _aOncology. | |
650 | 0 | _aMedical biochemistry. | |
650 | 0 | _aSurgery. | |
650 | 1 | 4 | _aMedicine & Public Health. |
650 | 2 | 4 | _aImaging / Radiology. |
650 | 2 | 4 | _aRadiotherapy. |
650 | 2 | 4 | _aOncology. |
650 | 2 | 4 | _aMedical Biochemistry. |
650 | 2 | 4 | _aSurgery. |
650 | 2 | 4 | _aPneumology/Respiratory System. |
700 | 1 |
_aBrown, J. Martin. _eeditor. |
|
700 | 1 |
_aMehta, Minesh P. _eeditor. |
|
700 | 1 |
_aNieder, Carsten. _eeditor. |
|
710 | 2 | _aSpringerLink (Online service) | |
773 | 0 | _tSpringer eBooks | |
776 | 0 | 8 |
_iPrinted edition: _z9783540256557 |
830 | 0 |
_aMedical Radiology, Radiation Oncology, _x0942-5373 |
|
856 | 4 | 0 | _uhttp://dx.doi.org/10.1007/3-540-35662-2 |
912 | _aZDB-2-SME | ||
950 | _aMedicine (Springer-11650) | ||
999 |
_c501999 _d501999 |