000			03266nam a22005415i 4500
001			978-1-59745-152-9
003			DE-He213
005			20161121230639.0
007			cr nn 008mamaa
008			100301s2006 xxu| s |||| 0|eng d
020			_a9781597451529 _9978-1-59745-152-9
024	7		_a10.1007/978-1-59745-152-9 _2doi
050		4	_aRC109-216
072		7	_aMJCJ _2bicssc
072		7	_aMED022090 _2bisacsh
082	0	4	_a616.9 _223
245	1	0	_aBacterial Genomes and Infectious Diseases _h[electronic resource] / _cedited by Voon L. Chan, Philip M. Sherman, Billy Bourke.
264		1	_aTotowa, NJ : _bHumana Press, _c2006.
300			_aXIV, 242 p. 42 illus., 1 illus. in color. _bonline resource.
336			_atext _btxt _2rdacontent
337			_acomputer _bc _2rdamedia
338			_aonline resource _bcr _2rdacarrier
347			_atext file _bPDF _2rda
505	0		_aMicrobial Genomes -- Evolution and Origin of Virulence Isolates -- Genomic Approach to Understanding Infectious Disease Mechanisms -- Knockout and Disease Models in Toll-Like Receptor-Mediated Immunity -- Campylobacter -- Genomics of Helicobacter Species -- The Organization of Leptospira at a Genomic Level -- Listeria monocytogenes -- Mycobacterial Genomes -- Mycoplasma -- Genome Comparisons of Diverse Staphylococcus aureus Strains -- Type III Secretion Systems in Yersinia pestis and Yersinia pseudotuberculosis -- Genomics and the Evolution of Pathogenic Vibrio cholerae -- Future Directions of Infectious Disease Research.
520			_aThe emergence and reemergence of infectious diseases, an increasing rate of antibiotic-resistant variants of pathogens, and the threat of bioterrorism underscore the importance of bacterial genomes and infectious diseases. Bacterial Genomes and Infectious Diseases presents major findings about bacterial genomes and their impact on strategy and approach for investigating mechanisms of pathogenesis of infectious diseases. This book imparts fundamental knowledge on the structure, organization, and evolution of bacterial genomes. The value and power of comparative genomics and proteomics, bioinformatics, microarrays, and knockout animal models in analyzing genomes, bacteria-host interactions and disease are demonstrated. Also discussed are the genomes of virulent and nonvirulent strains and species, origin and evolution of pathogens, different models of bacteria-host interactions, and diseases mechanisms.
650		0	_aMedicine.
650		0	_aImmunology.
650		0	_aMedical microbiology.
650		0	_aInfectious diseases.
650		0	_aMicrobiology.
650		0	_aMicrobial genetics.
650		0	_aMicrobial genomics.
650	1	4	_aMedicine & Public Health.
650	2	4	_aInfectious Diseases.
650	2	4	_aMedical Microbiology.
650	2	4	_aMicrobiology.
650	2	4	_aImmunology.
650	2	4	_aMicrobial Genetics and Genomics.
700	1		_aChan, Voon L. _eeditor.
700	1		_aSherman, Philip M. _eeditor.
700	1		_aBourke, Billy. _eeditor.
710	2		_aSpringerLink (Online service)
773	0		_tSpringer eBooks
776	0	8	_iPrinted edition: _z9781588294968
856	4	0	_uhttp://dx.doi.org/10.1007/978-1-59745-152-9
912			_aZDB-2-SME
950			_aMedicine (Springer-11650)
999			_c501856 _d501856